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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Proline derivatives >N-Boc-trans-4-Hydroxy-L-proline methyl ester

N-Boc-trans-4-Hydroxy-L-proline methyl ester

N-Boc-trans-4-Hydroxy-L-proline methyl ester Structure
  • ₹2200 - ₹9688.38
  • Product name: N-Boc-trans-4-Hydroxy-L-proline methyl ester
  • CAS: 74844-91-0
  • MF: C11H19NO5
  • MW: 245.27
  • EINECS:616-143-2
  • MDL Number:MFCD00076981
  • Synonyms:N-T-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER;N-(TERT-BUTOXYCARBONYL)-TRANS-HYDROXYL-L-PROLINE METHYL ESTER;N-ALPHA-T-BUTOXYCARBONYL-L-HYDROXYPROLINE METHYL ESTER;N-BOC-TRANS-4-HYDROXYL-L-PROLINE METHYL ESTER;N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER;N-BOC-L-TRANS-4-HYDROXY-PROLINE METHYL ESTER;(2R,4R)-4-HYDROXY-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER;(2S,4R)-1-(TERT-BUTOXYCARBONYL)-2-CARBOMETHOXY-4-HYDROXYPYRROLIDINE
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberB3843
  • Product descriptionN-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester min. 95.0 %
  • Packaging1G
  • Price₹2200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3843
  • Product descriptionN-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester min. 95.0 %
  • Packaging5G
  • Price₹6500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number639737
  • Product descriptionN-Boc-trans-4-hydroxy-L-proline methyl ester 97%
  • Packaging5G
  • Price₹9688.38
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B3843 N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester min. 95.0 % 1G ₹2200 2022-05-26 Buy
TCI Chemicals (India) B3843 N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester min. 95.0 % 5G ₹6500 2022-05-26 Buy
Sigma-Aldrich(India) 639737 N-Boc-trans-4-hydroxy-L-proline methyl ester 97% 5G ₹9688.38 2022-06-14 Buy

Properties

Melting point :92-96 °C (lit.)
alpha :-65 º (c=1 CHCl3)
Boiling point :132°C/0.05mmHg(lit.)
Density :1.216±0.06 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Soluble in chloroform, dichloromethane and ethyl acetate.
form :Crystalline Powder
pka :14.27±0.40(Predicted)
color :White to light beige
optical activity :[α]20/D -65°, c = 1% in chloroform
InChI :InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1
InChIKey :MZMNEDXVUJLQAF-SFYZADRCSA-N
SMILES :N1(C(OC(C)(C)C)=O)C[C@H](O)C[C@H]1C(OC)=O
LogP :0.813 at 25℃
CAS DataBase Reference :74844-91-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Description

It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

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Suppliers and manufacturers

BTC pharm India SYNARTIS PHARMA PVT LTD TEADUS PHARMA PRIVATE LIMITED ARRKEM LIFE SCIENCES PRIVATE LIMITED SV CHEM INTERMEDITES PRIVATE LIMITED JSK Chemicals Santo Righello Pvt. Ltd CLEARSYNTH LABS LTD. A.J Chemicals TCI Chemicals (India) Pvt. Ltd.