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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Borane >1-Methyl-4-pyrazole boronic acid pinacol ester

1-Methyl-4-pyrazole boronic acid pinacol ester

1-Methyl-4-pyrazole boronic acid pinacol ester Structure
  • ₹4800 - ₹61561.78
  • Product name: 1-Methyl-4-pyrazole boronic acid pinacol ester
  • CAS: 761446-44-0
  • MF: C10H17BN2O2
  • MW: 208.07
  • EINECS:616-293-9
  • MDL Number:MFCD03789259
  • Synonyms:1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-;1-METHYL- 4-PYRAZOLEBORONIC ACID PINACOL ESTER;1-METHYL-4-(4,4,5,5-TERAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOLE;1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-;1-Methyl-4-pyrazoleboronic acid pinacol ester, 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole;1-Methyl-4-(4,4,5-trimethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole;1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 97+%;2-(1-Methylpyrazol-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberM2339
  • Product description1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole min. 98.0 %
  • Packaging1G
  • Price₹4800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM2339
  • Product description1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole min. 98.0 %
  • Packaging5G
  • Price₹10800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number595314
  • Product description1-Methylpyrazole-4-boronic acid pinacol ester 95%
  • Packaging1G
  • Price₹5585.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number595314
  • Product description1-Methylpyrazole-4-boronic acid pinacol ester 95%
  • Packaging5G
  • Price₹21617.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number595314
  • Product description1-Methylpyrazole-4-boronic acid pinacol ester 95%
  • Packaging25G
  • Price₹61561.78
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M2339 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole min. 98.0 % 1G ₹4800 2022-05-26 Buy
TCI Chemicals (India) M2339 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole min. 98.0 % 5G ₹10800 2022-05-26 Buy
Sigma-Aldrich(India) 595314 1-Methylpyrazole-4-boronic acid pinacol ester 95% 1G ₹5585.7 2022-06-14 Buy
Sigma-Aldrich(India) 595314 1-Methylpyrazole-4-boronic acid pinacol ester 95% 5G ₹21617.53 2022-06-14 Buy
Sigma-Aldrich(India) 595314 1-Methylpyrazole-4-boronic acid pinacol ester 95% 25G ₹61561.78 2022-06-14 Buy

Properties

Melting point :59-64 °C(lit.)
Boiling point :308.3±15.0 °C(Predicted)
Density :1.05±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Chloroform (slightly), Methanol (Slightly)
pka :2.09±0.10(Predicted)
form :Crystals
color :Off-white to yellow
Water Solubility :Slightly soluble in water.
InChI :InChI=1S/C10H17BN2O2/c1-9(2)10(3,4)15-11(14-9)8-6-12-13(5)7-8/h6-7H,1-5H3
InChIKey :UCNGGGYMLHAMJG-UHFFFAOYSA-N
SMILES :N1(C)C=C(B2OC(C)(C)C(C)(C)O2)C=N1
CAS DataBase Reference :761446-44-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

It is a reagent used for Suzuki-Miyaura cross-coupling reactions, transesterification reactions. It is involved in several reactions as a reagent for the preparation of aminothiazoles as γ-secretase modulators,amino-pyrido-indol-carboxamides, as potential JAK2 inhibitors for myeloproliferative disorders therapy, pyridine derivatives as TGF-β1 and active A signaling inhibitors and MK-2461 analogs as inhibitors of c-Met kinase for the treatment of cancer.

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