8-pCPT-2μ-O-Me-cAMP
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- ₹24085.63 - ₹101733.35
- Product name: 8-pCPT-2μ-O-Me-cAMP
- CAS: 634207-53-7
- MF: C17H16ClN5NaO6PS
- MW: 507.82
- EINECS:
- MDL Number:MFCD23160251
- Synonyms:8-pCPT-2'-O-Me-Cyclic AMP (sodium salt);8-(4-Chlorophenylthio)-2μ-O-methyladenosine 3μ,5μ-cyclic monophosphate hydrate monosodium;8-pCPT-2μ-O-Me-cAMP;8-(4-Chlorophenylthio)-2′-O-methyladenosine 3′,5′-cyclic monophosphate monosodium hydrate;8-pCPT-2’-O-Me-cAMP
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberC8988
- Product description8-(4-Chlorophenylthio)-2′-O-methyladenosine 3′,5′-cyclic monophosphate monosodium hydrate ≥98% (HPLC)
- Packaging1MG
- Price₹24085.63
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberC8988
- Product description8-(4-Chlorophenylthio)-2′-O-methyladenosine 3′,5′-cyclic monophosphate monosodium hydrate ≥98% (HPLC)
- Packaging5MG
- Price₹101733.35
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C8988 | 8-(4-Chlorophenylthio)-2′-O-methyladenosine 3′,5′-cyclic monophosphate monosodium hydrate ≥98% (HPLC) | 1MG | ₹24085.63 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C8988 | 8-(4-Chlorophenylthio)-2′-O-methyladenosine 3′,5′-cyclic monophosphate monosodium hydrate ≥98% (HPLC) | 5MG | ₹101733.35 | 2022-06-14 | Buy |
Properties
Melting point :235.5-237.5 °C(lit.)
storage temp. :−20°C
solubility :H2O: >10mg/mL
form :solid
color :white
Water Solubility :Soluble to 100 mM in water
storage temp. :−20°C
solubility :H2O: >10mg/mL
form :solid
color :white
Water Solubility :Soluble to 100 mM in water
Safety Information
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Description
Exchange proteins activated by cAMP (Epacs) are guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-pCPT-2'-O-Me-Cyclic AMP is an 8-(4-chlorophenylthio) analog of cAMP that activates Epacs (AC50 = 1.8 μM). It is a super-activator of Epacs in that it dissociates GDP from Rap1 more strongly than the natural Epac agonist, cAMP. 8-pCPT-2'-O-Me-cAMP is strongly selective for Epac over the cAMP-activated kinase PKA. It does not discriminate between Epac1 and Epac2 and is used extensively to elucidate the roles of these Rap GEFs in cell function.More related product prices
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