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1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE

1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE Structure
  • ₹9960 - ₹48517.65
  • Product name: 1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE
  • CAS: 85532-75-8
  • MF: C21H21ClN2O
  • MW: 352.86
  • EINECS:
  • MDL Number:MFCD00069334
  • Synonyms:1-(2-chlorophenyl)-n-methyl-n-(1-methylpropyl)-3-isoquinolinecarboxamid ;n-methyl-n-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide ;1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE;PK 11195;1-(2-chlorophenyl)-N-methyl-*N-(1-methylpropyl)-3;PK 11195 PERIPHERAL BENZODIAZE;1-(2-Chlorophenyl)-N-(1-methylpropyl)-3-isoquinolinecarboxamide;chlorophenylmethyl(1-methylpropyl)isoquinolinecarboxamide
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Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberC0424
  • Product descriptionPK 11195
  • Packaging50MG
  • Price₹48517.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC0424
  • Product descriptionPK 11195
  • Packaging10MG
  • Price₹13444.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number5.05981
  • Product descriptionPK11195 - CAS 85532-75-8 - Calbiochem
  • Packaging10MG
  • Price₹9960
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C0424 PK 11195 50MG ₹48517.65 2022-06-14 Buy
Sigma-Aldrich(India) C0424 PK 11195 10MG ₹13444.65 2022-06-14 Buy
Sigma-Aldrich(India) 5.05981 PK11195 - CAS 85532-75-8 - Calbiochem 10MG ₹9960 2022-06-14 Buy

Properties

Boiling point :511.7±45.0 °C(Predicted)
Density :1.179±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 15 mg/ml).
form :White crystalline powder.
pka :1.76±0.50(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored under nitrogen or argon at -20° for up to 1 month.
CAS DataBase Reference :85532-75-8(CAS DataBase Reference)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Benzodiazepines bind two types of receptors, the central γ-aminobutyric acid A receptor and the peripheral translocator protein (TSPO). PK 11195 binds the peripheral benzodiazepine receptor, TSPO, with selectivity and high affinity (Ki = 3.1 nM in cerebellum, 4.1 nM in spinal cord). PK 11195, which lacks the 7-member heterocycle of diazepines, blocks binding of typical benzodiazepines to TSPO. In addition, the binding of labeled PK 11195 to tissues is used to detect the presence of TSPO by various methods. PK 11195 has been used to study the ligand binding site of the B. cereus TSPO.

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