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6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE

6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE Structure
  • ₹7400 - ₹82118.45
  • Product name: 6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE
  • CAS: 866405-64-3
  • MF: C24H25N5O
  • MW: 399.49
  • EINECS:
  • MDL Number:MFCD08705402
  • Synonyms:AMPK INHIBITOR;6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE;AMPK Inhibitor, Compound C, Dorsomorphin;6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidinedihydrochloride;Pyrazolo[1,5-a]pyriMidine, 6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-;DorsoMorphin, Free Base, >99%;6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrrazolo[1,5-a]pyrimidine;6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine
Price16 Properties Safety Information Description
16 prices
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Brand

  • Sigma-Aldrich
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 1MG
  • 2MG
  • 5MG
  • 10MG
  • 25MG
  • 50MG
  • ManufacturerSigma-Aldrich
  • Product number171261
  • Product descriptionInSolution AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem InSolution AMPK Inhibitor, Compound C, CAS 866405-64-3, is a 10 mM (1 mg/250 μl) solution of AMPK Inhibitor, Compound C (Cat. No. 171260) in DMSO.
  • Packaging1MG
  • Price₹13100
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number171260
  • Product descriptionAMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25.1, 148, and 234.6 nM, respectively).
  • Packaging1MG
  • Price₹14379.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number171264
  • Product descriptionInSolution AMPK Inhibitor, Compound C•2HCl - CAS 866405-64-3 - Calbiochem The InSolution AMPK Inhibitor, Compound C?2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/inhibitor is primarily used for Phosphorylation & D
  • Packaging2MG
  • Price₹17860
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number171260
  • Product descriptionAMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25.1, 148, and 234.6 nM, respectively).
  • Packaging5MG
  • Price₹40459.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number171260
  • Product descriptionAMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25.1, 148, and 234.6 nM, respectively).
  • Packaging10MG
  • Price₹62190.01
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD5394
  • Product descriptionDorsomorphin
  • Packaging10MG
  • Price₹7400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD5394
  • Product descriptionDorsomorphin
  • Packaging50MG
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number171261
  • Product descriptionInSolution AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem InSolution AMPK Inhibitor, Compound C, CAS 866405-64-3, is a 10 mM (1 mg/250 μl) solution of AMPK Inhibitor, Compound C (Cat. No. 171260) in DMSO.
  • Packaging1MG
  • Price₹13100
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number171260
  • Product descriptionAMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25
  • Packaging1MG
  • Price₹14379.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number171264
  • Product descriptionInSolution AMPK Inhibitor, Compound C•2HCl - CAS 866405-64-3 - Calbiochem The InSolution AMPK Inhibitor, Compound C?2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/i
  • Packaging2MG
  • Price₹17860
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP5499
  • Product descriptionDorsomorphin ≥98% (HPLC)
  • Packaging5MG
  • Price₹20654.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number171260
  • Product descriptionAMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25
  • Packaging5MG
  • Price₹40459.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number171260
  • Product descriptionAMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25
  • Packaging10MG
  • Price₹62190.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberP5499
  • Product descriptionDorsomorphin ≥98% (HPLC)
  • Packaging25MG
  • Price₹82118.45
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number D 9111
  • Product descriptionDorsomorphin 98%+
  • Packaging5mg
  • Price₹18090
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 9111
  • Product descriptionDorsomorphin 98%+
  • Packaging25mg
  • Price₹75006
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 171261 InSolution AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem InSolution AMPK Inhibitor, Compound C, CAS 866405-64-3, is a 10 mM (1 mg/250 μl) solution of AMPK Inhibitor, Compound C (Cat. No. 171260) in DMSO. 1MG ₹13100 2022-06-14 Buy
Sigma-Aldrich 171260 AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25.1, 148, and 234.6 nM, respectively). 1MG ₹14379.99 2022-06-14 Buy
Sigma-Aldrich 171264 InSolution AMPK Inhibitor, Compound C•2HCl - CAS 866405-64-3 - Calbiochem The InSolution AMPK Inhibitor, Compound C?2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/inhibitor is primarily used for Phosphorylation & D 2MG ₹17860 2022-06-14 Buy
Sigma-Aldrich 171260 AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25.1, 148, and 234.6 nM, respectively). 5MG ₹40459.99 2022-06-14 Buy
Sigma-Aldrich 171260 AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25.1, 148, and 234.6 nM, respectively). 10MG ₹62190.01 2022-06-14 Buy
TCI Chemicals (India) D5394 Dorsomorphin 10MG ₹7400 2022-05-26 Buy
TCI Chemicals (India) D5394 Dorsomorphin 50MG ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) 171261 InSolution AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem InSolution AMPK Inhibitor, Compound C, CAS 866405-64-3, is a 10 mM (1 mg/250 μl) solution of AMPK Inhibitor, Compound C (Cat. No. 171260) in DMSO. 1MG ₹13100 2022-06-14 Buy
Sigma-Aldrich(India) 171260 AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25 1MG ₹14379.99 2022-06-14 Buy
Sigma-Aldrich(India) 171264 InSolution AMPK Inhibitor, Compound C•2HCl - CAS 866405-64-3 - Calbiochem The InSolution AMPK Inhibitor, Compound C?2HCl, also referenced under CAS 866405-64-3, controls the biological activity of AMPK. This small molecule/i 2MG ₹17860 2022-06-14 Buy
Sigma-Aldrich(India) P5499 Dorsomorphin ≥98% (HPLC) 5MG ₹20654.1 2022-06-14 Buy
Sigma-Aldrich(India) 171260 AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25 5MG ₹40459.99 2022-06-14 Buy
Sigma-Aldrich(India) 171260 AMPK Inhibitor, Compound C - CAS 866405-64-3 - Calbiochem AMPK Inhibitor, Compound C, CAS 866405-64-3, is a cell-permeable compound that inhibits KDR/VEGFR2, ALK2/BMPR-I, and AMPK kinase activities (IC?? = 25 10MG ₹62190.01 2022-06-14 Buy
Sigma-Aldrich(India) P5499 Dorsomorphin ≥98% (HPLC) 25MG ₹82118.45 2022-06-14 Buy
ottokemi D 9111 Dorsomorphin 98%+ 5mg ₹18090 2022-05-26 Buy
ottokemi D 9111 Dorsomorphin 98%+ 25mg ₹75006 2022-05-26 Buy

Properties

Melting point :>228°C(dec.)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >2mg/mL (warmed)
pka :8.53±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P501 Dispose of contents/container to..…

Description

Dorsomorphin is a potent, reversible inhibitor of AMPK (Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCθ, PKA, and JAK3. Dorsomorphin can also dose-dependently inhibit the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK6). Independent of AMPK inhibition, dorsomorphin at 10 μM has additionally been shown to downregulate the Akt/mTOR pathway to induce autophagy in U251 human glioma cells.

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Suppliers and manufacturers

career henan chemical co
6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE
₹1.00 /1KG
6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE CAS:866405-64-3
CHEMSWORTH CLEARSYNTH LABS LTD. A.J Chemicals TCI Chemicals (India) Pvt. Ltd. Otto Chemie Pvt. Ltd. Clearsynth Labs
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences