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N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE

N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE Structure
  • ₹0
  • Product name: N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE
  • CAS: 868359-05-1
  • MF: C16H13BrF2N2O4
  • MW: 415.19
  • EINECS:
  • MDL Number:MFCD09971111
  • Synonyms:N-[4-(2-BROMO-4,5-DIFLUOROPHENOXY)PHENYL]-L-ASPARAGINE;WAY 213613;N4-[4-(2-Bromo-4,5-difluorophenoxy)phenyl)]-L-asparagine;(S)-2-amino-4-((4-(2-bromo-4,5-difluorophenoxy)phenyl)amino)-4-oxobutanoic acid;L-Asparagine, N-[4-(2-bromo-4,5-difluorophenoxy)phenyl]-;WAY 213613,WAY213613
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :565.6±50.0 °C(Predicted)
Density :1.664±0.06 g/cm3(Predicted)
storage temp. :Desiccate at RT
solubility :DMSO: >10mg/mL
form :white powder
pka :2.38±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

WAY 213613 is a strong, non-substrate inhibitor of EAAT2 (GLT-1) that displays > 44-fold selectivity over EAAT1 and EAAT3 (IC50 values are 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1 respectively). WAY 213613 exhibits no activity towards metabotropic and ionotropic glutamate receptors.

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