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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Esters >Ethyl compound >Diethyl ethoxymethylenemalonate

Diethyl ethoxymethylenemalonate

Diethyl ethoxymethylenemalonate  Structure
  • ₹891 - ₹9720.85
  • Product name: Diethyl ethoxymethylenemalonate
  • CAS: 87-13-8
  • MF: C10H16O5
  • MW: 216.23
  • EINECS:201-725-7
  • MDL Number:MFCD00009148
  • Synonyms:1,1-DICARBETHOXY-2-ETHOXYETHYLENE;2,2-DICARBETHOXYVINYL ETHYL ETHER;AKOS BBS-00004230;LABOTEST-BB LT02094814;ETHYL A-CARBETHOXY-B-ETHOXYACRYLATE;ETHYL ETHOXYMETHYLENE MALONATE;ETHYL 3-ETHOXY-2-(ETHOXYCARBONYL)ACRYLATE;(Ethoxymethylene)-propanedioic acid diethyl ester
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 1ML
  • 10ML
  • 25ML
  • 100gm
  • 100ML
  • 100G
  • 500gm
  • 500ML
  • 500G
  • ManufacturerTCI Chemicals (India)
  • Product numberE0255
  • Product descriptionDiethyl Ethoxymethylenemalonate min. 97.0 %
  • Packaging25ML
  • Price₹1500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberE0255
  • Product descriptionDiethyl Ethoxymethylenemalonate min. 97.0 %
  • Packaging100ML
  • Price₹2600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberE0255
  • Product descriptionDiethyl Ethoxymethylenemalonate min. 97.0 %
  • Packaging500ML
  • Price₹6900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD94208
  • Product descriptionDiethyl ethoxymethylenemalonate 99%
  • Packaging100G
  • Price₹1910
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number05689
  • Product descriptionDiethyl ethoxymethylenemalonate for LC-MS derivatization, LiChropur?, ≥97.0% (GC)
  • Packaging1ML
  • Price₹3442.35
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD94208
  • Product descriptionDiethyl ethoxymethylenemalonate 99%
  • Packaging500G
  • Price₹5098.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number05689
  • Product descriptionDiethyl ethoxymethylenemalonate for LC-MS derivatization, LiChropur?, ≥97.0% (GC)
  • Packaging10ML
  • Price₹9720.85
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number D 1715
  • Product descriptionDiethyl ethoxymethylidenemalonate, 99%
  • Packaging100gm
  • Price₹891
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 1715
  • Product descriptionDiethyl ethoxymethylidenemalonate, 99%
  • Packaging500gm
  • Price₹3195
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) E0255 Diethyl Ethoxymethylenemalonate min. 97.0 % 25ML ₹1500 2022-05-26 Buy
TCI Chemicals (India) E0255 Diethyl Ethoxymethylenemalonate min. 97.0 % 100ML ₹2600 2022-05-26 Buy
TCI Chemicals (India) E0255 Diethyl Ethoxymethylenemalonate min. 97.0 % 500ML ₹6900 2022-05-26 Buy
Sigma-Aldrich(India) D94208 Diethyl ethoxymethylenemalonate 99% 100G ₹1910 2022-06-14 Buy
Sigma-Aldrich(India) 05689 Diethyl ethoxymethylenemalonate for LC-MS derivatization, LiChropur?, ≥97.0% (GC) 1ML ₹3442.35 2022-06-14 Buy
Sigma-Aldrich(India) D94208 Diethyl ethoxymethylenemalonate 99% 500G ₹5098.58 2022-06-14 Buy
Sigma-Aldrich(India) 05689 Diethyl ethoxymethylenemalonate for LC-MS derivatization, LiChropur?, ≥97.0% (GC) 10ML ₹9720.85 2022-06-14 Buy
ottokemi D 1715 Diethyl ethoxymethylidenemalonate, 99% 100gm ₹891 2022-05-26 Buy
ottokemi D 1715 Diethyl ethoxymethylidenemalonate, 99% 500gm ₹3195 2022-05-26 Buy

Properties

Melting point :-33°C
Boiling point :279-283 °C(lit.)
Density :1.080 g/mL at 20 °C(lit.)
vapor pressure :<0.1 hPa
refractive index :n20/D 1.463
Flash point :311 °F
storage temp. :Store below +30°C.
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Liquid
color :Clear colorless to light yellow
Water Solubility :insoluble
BRN :880058
InChIKey :LTMHNWPUDSTBKD-UHFFFAOYSA-N
LogP :1.5-2.1 at pH7
CAS DataBase Reference :87-13-8(CAS DataBase Reference)
NIST Chemistry Reference :Propanedioic acid, (ethoxymethylene)-, diethyl ester(87-13-8)
EPA Substance Registry System :Propanedioic acid, (ethoxymethylene)-, diethyl ester (87-13-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Diethyl ethoxymethylenemalonate is used for synthesis of pyrido[3,2-e]pyrimido[1,2-c]pyrimidines. Initially, it was used to monitor lysine decarboxylase activity. It is useful in the determination of amino acids by precolumn derivatization by using reversed-phase high-performance liquid chromatography (HPLC). It plays an important role in the Gould-Jacobs reaction to prepare quinolines. For example, anile reacts with this reagent to give 4-hydroxyquinoline. It acts as an intermediate in the production of flumequine, which is a fluoroquinolone antibiotic.

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