Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P305+P351+P338
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378
In case of fire: Use … for extinction.
P403+P235
Store in a well-ventilated place. Keep cool.
Description
8(S)-HETE is a polyunsaturated fatty acid chemotactic for neutrophils and an intermediate in the synthesis of the family of eicosanoids known as leukotrienes. The compound has been observed to be biosynthesized in human neutrophils, phorbol ester-treated mouse epidermis and by hepatic microsomal cytochrome P-4503. 8(S)-HETE has been observed to regulate epithelial cell migration in the rat cornea. The compound has also been recognized as the key component of arachidonic acid in corneal wound healing. Evidence demonstrates 8(S)-HETE activates PPARα and PKC.