DIACYLGLYCEROL KINASE INHIBITOR I
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- ₹11247.18 - ₹36783.35
- Product name: DIACYLGLYCEROL KINASE INHIBITOR I
- CAS: 93076-89-2
- MF: C27H26FN3OS
- MW: 459.58
- EINECS:
- MDL Number:MFCD00055114
- Synonyms:DIACYLGLYCEROL KINASE;DIACYLGLYCEROL KINASE INHIBITOR I;DIACYLGLYCEROL KINASE INHIBITOR I (R59 022);DAGK;DAG KINASE;EC 2.7.1.107;EC: 2.7.1.107;DKI
3 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberD5919
- Product descriptionDiacylglycerol Kinase Inhibitor I solid
- Packaging5MG
- Price₹36783.35
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number266785
- Product descriptionDiacylglycerol Kinase Inhibitor I - CAS 93076-89-2 - Calbiochem The Diacylglycerol Kinase Inhibitor I, also referenced under CAS 93076-89-2, controls the biological activity of Diacylglycerol Kinase. This small mol
- Packaging5MG
- Price₹15469.99
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberD5919
- Product descriptionDiacylglycerol Kinase Inhibitor I solid
- Packaging1MG
- Price₹11247.18
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D5919 | Diacylglycerol Kinase Inhibitor I solid | 5MG | ₹36783.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 266785 | Diacylglycerol Kinase Inhibitor I - CAS 93076-89-2 - Calbiochem The Diacylglycerol Kinase Inhibitor I, also referenced under CAS 93076-89-2, controls the biological activity of Diacylglycerol Kinase. This small mol | 5MG | ₹15469.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D5919 | Diacylglycerol Kinase Inhibitor I solid | 1MG | ₹11247.18 | 2022-06-14 | Buy |
Properties
Boiling point :619.8±65.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :0.1 M HCl: slightly soluble
form :solid
pka :7.76±0.20(Predicted)
color :pale yellow
biological source :synthetic (organic)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :0.1 M HCl: slightly soluble
form :solid
pka :7.76±0.20(Predicted)
color :pale yellow
biological source :synthetic (organic)
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Description
Diacylglycerol (DAG) kinases (DGKs) phosphorylate DAG to give phosphatidic acid (PA), reducing signaling through DAG and increasing signaling through PA. R-59-022 is an inhibitor of DGK (IC50 = 2.8 μM). This results in increased DAG-dependent PKC activity and potentiates aggregation of thrombin-stimulated platelets. R-59-022 also blocks vascular contraction induced by the thromboxane analog U-46619 . At 10 μM, R-59-022 induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells. It inhibits DGK-θ in vitro at concentrations below 1 μM and blocks DGK-θ activity in vivo. R-59-022 also inhibits A. thaliana DGK2 (IC50 = 50 μM) and suppresses root growth but does not affect DGK7 at 50 μM.Related product price
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