ACK1-B19
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- ₹0
- Product name: ACK1-B19
- CAS: 1234480-46-6
- MF: C24H27N7O2
- MW: 445.52
- EINECS:
- MDL Number:MFCD30742941
- Synonyms:ACK1-B19;XMD8-87;CS-2588;XMD-8-87;XMD8 87;XMD 8 87;2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one;6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-;XMD8-87 (ACK1-B19)
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
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Properties
Density :1.283±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :10.18±0.20(Predicted)
color :White to yellow
storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :10.18±0.20(Predicted)
color :White to yellow
Safety Information
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Description
XMD8-87 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2) with an IC50 value of 1.9 μM in HEK293T cells expressing human TNK2. It is selective for TNK2 over a panel of approximately 100 kinases with >90 and <50% inhibition for TNK2 and all other kinases tested, respectively. XMD8-87 inhibits growth of Ba/F3 cells expressing constitutively active mutant TNK2s (IC50s = 0.1-77 nM) commonly found in leukemias but has no effect on cells expressing wild-type TNK2 (IC50 = >1 μM).Related product price
- XMD17 109
₹14241.3-57142.8
Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Zeye Biotechnology Co., Ltd.