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AMASTATIN HYDROCHLORIDE

AMASTATIN HYDROCHLORIDE Structure
  • ₹12524.53 - ₹230789
  • Product name: AMASTATIN HYDROCHLORIDE
  • CAS: 100938-10-1
  • MF: C21H39ClN4O8
  • MW: 511.01
  • EINECS:999-999-2
  • MDL Number:MFCD00058071
  • Synonyms:[(2S,3R)-3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP HYDROCHLORIDE;(2S,3R)-[3-AMINO-2-HYDROXY-5-METHYLHEXANOYL]-VAL-VAL-ASP-OH HCL;AMASTATIN HYDROCHLORIDE;AMASTATIN HYDROCHLORIDE HYDRATE;H-(2S,3R)-AHMH-VAL-VAL-ASP-OH HCL;N((2S 3R)3-AMINO-2-HXY-5-ME.HEXANOYL)-L&;Amastatinhydrochloridebiochemikasynthetic;(2s,3r)-3-amino-2-hydroxy-5-methylhexanoyl-val-val-asp hydrochloride hydrate
5 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 0.5MG
  • 1MG
  • 5MG
  • 10MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberA1276
  • Product descriptionAmastatin hydrochloride hydrate ≥97% (HPLC)
  • Packaging0.5MG
  • Price₹12524.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA1276
  • Product descriptionAmastatin hydrochloride hydrate ≥97% (HPLC)
  • Packaging1MG
  • Price₹20892.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA1276
  • Product descriptionAmastatin hydrochloride hydrate ≥97% (HPLC)
  • Packaging5MG
  • Price₹69756.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA1276
  • Product descriptionAmastatin hydrochloride hydrate ≥97% (HPLC)
  • Packaging10MG
  • Price₹124963.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA1276
  • Product descriptionAmastatin hydrochloride hydrate ≥97% (HPLC)
  • Packaging25MG
  • Price₹230789
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 0.5MG ₹12524.53 2022-06-14 Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 1MG ₹20892.25 2022-06-14 Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 5MG ₹69756.3 2022-06-14 Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 10MG ₹124963.8 2022-06-14 Buy
Sigma-Aldrich(India) A1276 Amastatin hydrochloride hydrate ≥97% (HPLC) 25MG ₹230789 2022-06-14 Buy

Properties

Melting point :202-205 °C
storage temp. :-20°C
solubility :methanol: 5 mg/mL, clear, colorless
form :White to off-white powder.
color :White to off-white
BRN :8888370

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Amastatin is a slow, tight binding, competitive aminopeptidase (AP) inhibitor, first described as an inhibitor of human serum AP-A (glutamyl AP; IC50 = 0.54 μg/ml) but not of AP-B (arginine AP). It also inhibits AP-N (AP-M, alanyl AP; Ki = 20-200 nM), leucyl-cystinyl AP (Ki = 20-220 nM), and endoplasmic reticulum AP 1 (Ki = 41.8 μM). Amastatin is without effect on trypsin, papain, chymotrypsin, elastase, pepsin, or thermolysin.

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