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ANTIBIOTIC UCN-02

ANTIBIOTIC UCN-02 Structure
  • ₹0
  • Product name: ANTIBIOTIC UCN-02
  • CAS: 121569-61-7
  • MF: C28H26N4O4
  • MW: 482.53
  • EINECS:
  • MDL Number:MFCD32174062
  • Synonyms:UCN-02;ANTIBIOTIC UCN-02;9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, (3S,9S,10R,11R,13R)-;UCN02,UCN 02
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Properties

Boiling point :705.7±60.0 °C(Predicted)
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :solution in ethanol.
pka :12.25±0.70(Predicted)
color :Colorless to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

UCN-02 is a indolocarbazole isolated from a high staurosporine-producing Streptomyces culture. UCN-02 is isolated as a minor co-metabolite of high staurosporine-producing strains of selected actinomycetes. Although less selective than its isomer UCN-01, UCN-02 exhibits comparable activity and probably acts by similar mechanisms. UCN-02 is an inhibitor of PKC α, PKC β, PKC δ, PKCε and PKC γ.

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