ASARININ
- ₹0
- Product name: ASARININ
- CAS: 133-04-0
- MF: C20H18O6
- MW: 354.35
- EINECS:
- MDL Number:MFCD00198067
- Synonyms:(-)-SESAMINE;(-)-ASARININ;ASARININ;EPI-SESAMIN;(-)-5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[1,3-benzodioxole];5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(1,3-benzodioxole);L-Asarinin;5-[4-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-1-yl]-1,3-benzodioxole
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Properties
Melting point :121°
alpha :D20 -118.6°; D23 -122° (chloroform)
Boiling point :504.4±50.0 °C(Predicted)
Density :1.385±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly, Sonicated)
form :Solid
color :White to Off-White
alpha :D20 -118.6°; D23 -122° (chloroform)
Boiling point :504.4±50.0 °C(Predicted)
Density :1.385±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly, Sonicated)
form :Solid
color :White to Off-White
Safety Information
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Description
Asarinin is a lignan that has been found in A. sieboldii. It is an epimer of sesamin and a noncompetitive inhibitor of Δ5-desaturase (Ki = 0.28 mM). It is selective for Δ5-desaturase over Δ6- and Δ9-desaturase. Asarinin is cytotoxic to A2780 and SKOV3 ovarian cancer cells (IC50s = 38.45 and 60.87 μM, respectively) but not immortalized ovarian surface epithelial cells (IC50 = >200 μM). It induces apoptosis and activates caspase-3, -8, and -9 in A2780 and SKOV3 cells.Related product price
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₹2100-297817.4
Suppliers and manufacturers
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Chongqing Chemdad Co., Ltd
Hubei Ipure Biology Co., Ltd
Hefei TNJ Chemical Industry Co.,Ltd.
ANHUI WITOP BIOTECH CO., LTD
Dayang Chem (Hangzhou) Co.,Ltd.