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ChemicalBook > Product Catalogue >Natural Products >Lignans >ASARININ

ASARININ

ASARININ Structure
  • ₹0
  • Product name: ASARININ
  • CAS: 133-04-0
  • MF: C20H18O6
  • MW: 354.35
  • EINECS:
  • MDL Number:MFCD00198067
  • Synonyms:(-)-SESAMINE;(-)-ASARININ;ASARININ;EPI-SESAMIN;(-)-5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[1,3-benzodioxole];5,5'-[(1R,3aα,4S,6aα)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(1,3-benzodioxole);L-Asarinin;5-[4-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-1-yl]-1,3-benzodioxole
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :121°
alpha :D20 -118.6°; D23 -122° (chloroform)
Boiling point :504.4±50.0 °C(Predicted)
Density :1.385±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly, Sonicated)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Asarinin is a lignan that has been found in A. sieboldii. It is an epimer of sesamin and a noncompetitive inhibitor of Δ5-desaturase (Ki = 0.28 mM). It is selective for Δ5-desaturase over Δ6- and Δ9-desaturase. Asarinin is cytotoxic to A2780 and SKOV3 ovarian cancer cells (IC50s = 38.45 and 60.87 μM, respectively) but not immortalized ovarian surface epithelial cells (IC50 = >200 μM). It induces apoptosis and activates caspase-3, -8, and -9 in A2780 and SKOV3 cells.

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Suppliers and manufacturers

career henan chemical co
ASARININ
₹1.00 /1KG
ASARININ CAS:133-04-0
TargetMol Chemicals Inc.
(-)-Asarinin
₹120.00 /20mg
(-)-Asarinin CAS:133-04-0
Henan Tianfu Chemical Co.,Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Hubei Ipure Biology Co., Ltd
Hefei TNJ Chemical Industry Co.,Ltd.
ANHUI WITOP BIOTECH CO., LTD
Dayang Chem (Hangzhou) Co.,Ltd.
Labnetwork lnc.