ASPERULOSIDE
- ₹24518.63
- Product name: ASPERULOSIDE
- CAS: 14259-45-1
- MF: C18H22O11
- MW: 414.36
- EINECS:238-137-5
- MDL Number:MFCD31725921
- Synonyms:ASPERULOSIDE;RUBICHLORIC ACID;[2aS-(2aalpha,4aalpha,5alpha,7balpha)]-5-(beta-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-1-oxo-1H-2,6-dioxacyclopent[cd]inden-4-ylmethyl acetate ;1H-2,6-Dioxacyclopentcdinden-1-one, 4-(acetyloxy)methyl-5-(.beta.-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)-;(2aS)-2a,4aα,5,7bα-Tetrahydro-4-acetoxymethyl-5α-(β-D-glucopyranosyloxy)-1H-2,6-dioxacyclopent[cd]inden-1-one;(2As-(2aalpha,4aalpha,5alpha,7balpha))-5-(beta-D-glucopyranosyloxy)-2A,4A,5,7B-tetrahydro-1-oxo-1H-2,6-dioxacyclopent(cd)inden-4-ylmethyl acetate;1H-2,6-Dioxacyclopent(cd)inden-1-one, 4-((acetyloxy)methyl)-5-(beta-D-glucopyranosyloxy)-2A,4A,5,7B-tetrahydro-, (2as-(2aalpha,5alpha,7balpha))-;Einecs 238-137-5
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- ManufacturerSigma-Aldrich(India)
- Product numberSMB00085
- Product descriptionAsperuloside ≥95% (LC/MS-ELSD)
- Packaging1MG
- Price₹24518.63
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SMB00085 | Asperuloside ≥95% (LC/MS-ELSD) | 1MG | ₹24518.63 | 2022-06-14 | Buy |
Properties
Melting point :131-132°
alpha :D25 -198.6° (c = 1.44 in water)
Boiling point :704.2±60.0 °C(Predicted)
Density :1.62±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in methanol and water
form :powder
pka :12.76±0.70(Predicted)
color :White
EPA Substance Registry System :1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(?-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)- (14259-45-1)
alpha :D25 -198.6° (c = 1.44 in water)
Boiling point :704.2±60.0 °C(Predicted)
Density :1.62±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in methanol and water
form :powder
pka :12.76±0.70(Predicted)
color :White
EPA Substance Registry System :1H-2,6-Dioxacyclopent[cd]inden-1-one, 4-[(acetyloxy)methyl]-5-(?-D-glucopyranosyloxy)-2a,4a,5,7b-tetrahydro-, (2aS,4aS,5S,7bS)- (14259-45-1)
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
Asperuloside is an iridoid glycoside that has been found in G. tunetanum and has diverse biological activities, including anti-angiogenic, anti-inflammatory, and anti-obesity properties. It reduces microvessel formation by 67% in a chick embryo chorioallantoic membrane assay when used at a concentration of 2 μg/egg. Asperuloside (20, 40, and 80 mg/L) inhibits LPS-induced increases in TNF-α, IL-1β, and IL-6 production in RAW 264.7 macrophages in a concentration-dependent manner. It reduces lung myeloperoxidase (MPO) activity and bronchoalveolar lavage fluid (BALF) levels of TNF-α, IL-1β, and IL-6 in a mouse model of LPS-induced acute lung injury when administered at doses of 20, 40, and 80 mg/kg. Dietary administration of asperuloside decreases body weight gain, white adipose tissue (WAT) weight, and the ratio of WAT weight to body weight in a high-fat diet-induced mouse model of metabolic syndrome.More related product prices
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