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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >AURANTIO-OBTUSIN

AURANTIO-OBTUSIN

AURANTIO-OBTUSIN Structure
  • ₹0
  • Product name: AURANTIO-OBTUSIN
  • CAS: 67979-25-3
  • MF: C17H14O7
  • MW: 330.29
  • EINECS:
  • MDL Number:MFCD13194886
  • Synonyms:1,3,7-Trihydroxy-2,8-diMethoxy-6-Methyl-9,10-anthracenedione;Aurantio-obtusifolin;AURANTIO-OBTUSIN;1,3,7-Trihydroxy-2,8-dimethoxy-6-methylanthracene-9,10-dione;URANTIO-OBTUSIN;Aurantioobtusin, 98%, from Catsia tora Linn;9,10-Anthracenedione, 1,3,7-trihydroxy-2,8-dimethoxy-6-methyl-;67979-25-3 AURANTIO-OBTUSIN
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :265-266 °C
Boiling point :594.6±50.0 °C(Predicted)
Density :1.510±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble in chloroform, DMSO and methan
form :powder
pka :6.32±0.20(Predicted)
color :Orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Aurantioobtusin is an anthraquinone originally isolated from Cassia seeds with diverse biological activities. It inhibits rat lens aldose reductase (RLAR) in vitro (IC50 = 13.6 μM). Aurantioobtusin (10 and 100 μM) activates the aryl hydrocarbon receptor (AhR) in a concentration-dependent manner. It inhibits rat platelet aggregation induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607), ADP, and collagen. Aurantioobtusin induces vasorelaxation in isolated precontracted rat mesenteric artery rings, an effect that is inhibited by the PI3K inhibitor LY290042 or inhibition of endothelial nitric oxide synthase (eNOS). It is larvicidal against A. gambiae mosquitoes (LD50 = 10 ppm).

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