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ChemicalBook > Product Catalogue >Organic Chemistry >Diazo,azo Or azoxy Compounds >AZASERINE

AZASERINE

AZASERINE Structure
  • ₹2619.65 - ₹58487.48
  • Product name: AZASERINE
  • CAS: 115-02-6
  • MF: C5H7N3O4
  • MW: 173.13
  • EINECS:204-061-6
  • MDL Number:MFCD00036802
  • Synonyms:serine,diazoacetate(ester) ;O-DIAZOACETYL-L-SERINE;azaserin ;ci337 ;ci-337 ;cl337 ;cn-15,757 ;2-aMino-3-(2-diazoacetoxy)propanoic acid
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 0.5MG
  • 50MG
  • 250MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberA4142
  • Product descriptionAzaserine ≥98% (TLC)
  • Packaging250MG
  • Price₹58487.48
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA4142
  • Product descriptionAzaserine ≥98% (TLC)
  • Packaging50MG
  • Price₹21639.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA1164
  • Product descriptionAzaserine Hybri-Max?, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma
  • Packaging0.5MG
  • Price₹2619.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A4142 Azaserine ≥98% (TLC) 250MG ₹58487.48 2022-06-14 Buy
Sigma-Aldrich(India) A4142 Azaserine ≥98% (TLC) 50MG ₹21639.18 2022-06-14 Buy
Sigma-Aldrich(India) A1164 Azaserine Hybri-Max?, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma 0.5MG ₹2619.65 2022-06-14 Buy

Properties

Melting point :146-162° (dec)
alpha :D27.5 -0.5° (c = 8.46% in H2O at pH 5.18)
Boiling point :303.75°C (rough estimate)
Density :1.5830 (rough estimate)
refractive index :1.6190 (estimate)
storage temp. :2-8°C
solubility :H2O: 50 mg/mL, clear, yellow
form :lyophilized powder
pka :8.55(at 25℃)
color :Light-yellow needles from EtOH (aq)
Merck :13,902
BRN :1726602
IARC :2B (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Azaserine (115-02-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.

Description

Azaserine is a tumor-inhibiting antibiotic isolated from a species of Streptomyces that functions as a glutamine analog. At 25 μM, it inhibits the glutamine-dependent amidotransferases involved in nucleotide biosynthesis, phosphoribosylformylglycinamidine synthetase and glucosamine-6-phosphate isomerase. Azaserine also inhibits the hexosamine biosynthetic pathway, which shunts excessive intracellular glucose into the biosynthesis of UDP-N-acetylglucosamine and the formation of O-linked glycoproteins. Azaserine has been shown to protect against hyperglycemic endothelial damage through its antioxidant effects.

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