AZASERINE
- CAS No.
- 115-02-6
- Chemical Name:
- AZASERINE
- Synonyms
- azs;ci337;cl337;p-165;ci-337;nsc-742;cn15757;azaserin;AZASERINE;cn-15,757
- CBNumber:
- CB3388053
- Molecular Formula:
- C5H7N3O4
- Molecular Weight:
- 173.13
- MOL File:
- 115-02-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/10/28 23:16:16
| Melting point | 146-162° (dec) |
|---|---|
| alpha | D27.5 -0.5° (c = 8.46% in H2O at pH 5.18) |
| Boiling point | 303.75°C (rough estimate) |
| Density | 1.5830 (rough estimate) |
| refractive index | 1.6190 (estimate) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL, clear, yellow |
| form | lyophilized powder |
| pka | 8.55(at 25℃) |
| color | Light-yellow needles from EtOH (aq) |
| optical activity | -0.527.5 (H2O) |
| Merck | 13,902 |
| BRN | 1726602 |
| IARC | 2B (Vol. 10, Sup 7) 1987 |
| EPA Substance Registry System | Azaserine (115-02-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H351 | |||||||||
| Precautionary statements | P201-P301+P310+P330 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25-40 | |||||||||
| Safety Statements | 53-36/37/39-45 | |||||||||
| RIDADR | UN 3462 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VT9625000 | |||||||||
| F | 10 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| Toxicity | LD50 in mice, rats (mg/kg/day): 150, 170 orally (Sternberg, Philips) | |||||||||
| NFPA 704 |
|
AZASERINE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | A4142 | Azaserine ≥98% (TLC) | 115-02-6 | 50MG | ₹21639.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A4142 | Azaserine ≥98% (TLC) | 115-02-6 | 250MG | ₹58487.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | A1164 | Azaserine Hybri-Max?, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma | 115-02-6 | 0.5MG | ₹2619.65 | 2022-06-14 | Buy |
AZASERINE Chemical Properties,Uses,Production
Chemical Properties
Light-yellow needles from EtOH.
Uses
antineoplastic, amino acid antagonist
Definition
ChEBI: A carboxylic ester resulting from the formal condensation of the carboxy group of diazoacetic acid with the alcoholic hydroxy group of L-serine. An antibiotic produced by a Streptomyces species.
General Description
Pale yellow to green crystals. Used as an antifungal agent.
Air & Water Reactions
Very soluble in water.
Reactivity Profile
AZASERINE is incompatible with acids.
Hazard
Toxic; possible carcinogen; neoplastigenic; tumorigenic; poison; teratogen; mutagen.
Safety Profile
Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
Crystallise azaserine from 90% EtOH. Also dissolve it in H2O, filter it through Supercel and add EtOH to give azaserine as pale yellow crystals. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 1 pp 75-76 1961, Curphey & David J Org Chem 43 4666 1978, Beilstein 4 IV 3124.]
AZASERINE Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | China | 9220 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29815 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 23325 | 58 | Inquiry |
| BOC Sciences | 16314854226; +16314854226 | United States | 19741 | 58 | Inquiry |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | China | 3135 | 58 | Inquiry |
| TargetMol Chemicals Inc. | United States | 38463 | 58 | Inquiry | |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43340 | 58 | Inquiry |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33338 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57505 | 58 | Inquiry |
115-02-6(AZASERINE)Related Search:
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