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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Acarbose

Acarbose

Acarbose Structure
  • ₹6400 - ₹27657.88
  • Product name: Acarbose
  • CAS: 56180-94-0
  • MF: C25H43NO18
  • MW: 645.61
  • EINECS:260-030-7
  • MDL Number:MFCD00869592
  • Synonyms:4)-O-a-D-glucopyranosyl-(1®D-Glucose,O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino]-a-D-glucopyranosyl-(1®Acarbose (Acarbosum);(2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-;O-4,6-Dideoxy-4-[[[1S-(1α,4α,5β,6α)]-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino]-α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-glucose;Acarbose API;O-4,6-DIDEOXY-4-[[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-2-CYCLOHEXEN-1-YL]AMINO]-ALPHA-D-GLUCOPYRANOSYL-(1-4)-O-ALPHA-D-GLUCOPYRANOSYL-(1-4)-D-GLUCOSE;5-[5-[3,4-DIHYDROXY-6-METHYL-5-[[4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-1-CYCLOHEX-2-ENYL]AMINO]OXAN-2-YL]OXY-3,4-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY-6-(HYDROXYMETHYL)OXANE-2,3,4-TRIOL
Price7 Properties Safety Information Description
7 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)
  • ottokemi
  • SRL

Package

  • 500MG
  • 1gm
  • 1G
  • 5G
  • 1Gms
  • 5Gms
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1253
  • Product descriptionAcarbose Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹11593.58
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA8980
  • Product descriptionAcarbose ≥95%
  • Packaging1G
  • Price₹27657.88
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2485
  • Product descriptionAcarbose
  • Packaging1G
  • Price₹6800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2485
  • Product descriptionAcarbose
  • Packaging5G
  • Price₹19100
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number A 0855
  • Product descriptionAcarbose, ≥95%
  • Packaging1gm
  • Price₹24903
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number65457
  • Product descriptionAcarbose extrapure, 95%
  • Packaging5Gms
  • Price₹20000
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number65457
  • Product descriptionAcarbose extrapure, 95%
  • Packaging1Gms
  • Price₹6400
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PHR1253 Acarbose Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹11593.58 2022-06-14 Buy
Sigma-Aldrich(India) A8980 Acarbose ≥95% 1G ₹27657.88 2022-06-14 Buy
TCI Chemicals (India) A2485 Acarbose 1G ₹6800 2022-05-26 Buy
TCI Chemicals (India) A2485 Acarbose 5G ₹19100 2022-05-26 Buy
ottokemi A 0855 Acarbose, ≥95% 1gm ₹24903 2022-05-26 Buy
SRL 65457 Acarbose extrapure, 95% 5Gms ₹20000 2022-05-26 Buy
SRL 65457 Acarbose extrapure, 95% 1Gms ₹6400 2022-05-26 Buy

Properties

Melting point :165-170°C
alpha :D18 +165° (c = 0.4 in water)
Boiling point :675.05°C (rough estimate)
Density :1.4278 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :Very soluble in water, soluble in methanol, practically insoluble in methylene chloride.
form :Solid
pka :12.39±0.20(Predicted)
color :White to Off-White
Water Solubility :Soluble in water.
Merck :14,18
Stability :Hygroscopic
InChIKey :XUFXOAAUWZOOIT-JMPDRRIHSA-N
LogP :-7.935 (est)
CAS DataBase Reference :56180-94-0

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Acarbose is the first identified α-glucosidase inhibitor. It has been shown to delay the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase and sucrase with IC50 values of 0.16 and 2.9 μM, respectively. It has also been shown to bind to phosphorylase kinase, potentiating its activity. In clinical trials, acarbose has been used to inhibit postprandial hyperglycemia associated with diabetes without cardiovascular complications.

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Suppliers and manufacturers

ANWITA APIS Vijaya Pharma And Life Science OCEAN TRADING CORPORATION VIVAN Life Sciences Pvt. Limited. TCI Chemicals (India) Pvt. Ltd. Otto Chemie Pvt. Ltd. Alfa Aesar Sisco Research Laboratories Pvt. Ltd. Pharmaffiliates Analytics and Synthetics P. Ltd Triveni chemicals