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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antiviral drugs >Acyclovir

Acyclovir

Acyclovir Structure
  • ₹3600 - ₹79282.3
  • Product name: Acyclovir
  • CAS: 59277-89-3
  • MF: C8H11N5O3
  • MW: 225.2
  • EINECS:261-685-1
  • MDL Number:MFCD00057880
  • Synonyms:1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-6h-purin-6-on ;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)-methyl)-6h-purin-6-on ;aciclovirum(latin) ;acielovir;cycloguanosine;Zoviax;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6h-purin-6-one;2-AMINO-9-(2-HYDROXY-ETHOXYMETHYL)-1,9-DIHYDRO-PURIN-6-ONE
Price7 Properties Safety Information Description
7 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 100MG
  • 500MG
  • 1G
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberA1915
  • Product descriptionAcyclovir
  • Packaging1G
  • Price₹3600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA1915
  • Product descriptionAcyclovir
  • Packaging5G
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA1915
  • Product descriptionAcyclovir
  • Packaging25G
  • Price₹21500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1254
  • Product descriptionAcyclovir Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹8356.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA4669
  • Product descriptionAcycloguanosine ≥99% (HPLC), powder
  • Packaging50MG
  • Price₹11355.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA4669
  • Product descriptionAcycloguanosine ≥99% (HPLC), powder
  • Packaging100MG
  • Price₹20015.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA4669
  • Product descriptionAcycloguanosine ≥99% (HPLC), powder
  • Packaging500MG
  • Price₹79282.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A1915 Acyclovir 1G ₹3600 2022-05-26 Buy
TCI Chemicals (India) A1915 Acyclovir 5G ₹9800 2022-05-26 Buy
TCI Chemicals (India) A1915 Acyclovir 25G ₹21500 2022-05-26 Buy
Sigma-Aldrich(India) PHR1254 Acyclovir Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹8356.9 2022-06-14 Buy
Sigma-Aldrich(India) A4669 Acycloguanosine ≥99% (HPLC), powder 50MG ₹11355.43 2022-06-14 Buy
Sigma-Aldrich(India) A4669 Acycloguanosine ≥99% (HPLC), powder 100MG ₹20015.43 2022-06-14 Buy
Sigma-Aldrich(India) A4669 Acycloguanosine ≥99% (HPLC), powder 500MG ₹79282.3 2022-06-14 Buy

Properties

Melting point :256-257°C
Boiling point :366.71°C (rough estimate)
Density :1.3654 (rough estimate)
refractive index :1.8000 (estimate)
storage temp. :2-8°C
solubility :H2O: 0.7 mg/mL
form :powder
pka :pKa 2.27 (Uncertain);9.25 (Uncertain)
color :white
Water Solubility :Soluble in 1M HCl at 50mg/ml. Soluble in water at 0.7mg/ml. Also soluble in DMSO
Merck :14,146
BCS Class :4,3
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :MKUXAQIIEYXACX-UHFFFAOYSA-N
LogP :-0.617 (est)
CAS DataBase Reference :59277-89-3(CAS DataBase Reference)
IARC :3 (Vol. 76) 2000

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.

Description

Acyclovir is a guanosine analog with antiviral activity in vitro against the herpes simplex viruses, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpes virus 6 (ID50s = 0.1 - 63.1 μM). Acyclovir differs from most nucleoside analogs in that it contains only a partial nucleoside structure with an acyclic side chain. It diffuses freely into cells and is selectively converted into acyclo-guanosine monophosphate by a virus-specific thymidine kinase. During DNA replication, the phosphorylated form of acyclovir is preferentially incorporated into viral DNA, resulting in premature chain termination and inhibition of further activity of DNA polymerase.

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