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Alvespimycin

Alvespimycin Structure
  • ₹38709 - ₹5288674
  • Product name: Alvespimycin
  • CAS: 467214-20-6
  • MF: C32H48N4O8
  • MW: 616.75
  • EINECS:
  • MDL Number:MFCD08457919
  • Synonyms:17-DIMETHYLAMINOETHYLAMINO-17-DEMETHOXYG;17-DMAGhydrochloride;Alvespimycin;17-DMAG (Alvespimycin);Unii-001L2fe0m3;17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycinhydrochloride;17-N-(2-DiMethylaMinoethylaMino)-17-deMethoxy GeldanaMycin;17-N-(2-DiMethylaMinoethylaMino)-17-deMethoxy GeldanaMycin-d6
Price2 Properties Safety Information Description
2 prices
Selected condition：

Brand

  • ottokemi

Package

  • 1mg
  • 5mg
  • Manufacturerottokemi
  • Product number D 8505
  • Product description17-DMAG ≥98%
  • Packaging1mg
  • Price₹38709
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 8505
  • Product description17-DMAG ≥98%
  • Packaging5mg
  • Price₹5288674
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ottokemi D 8505 17-DMAG ≥98% 1mg ₹38709 2022-05-26 Buy
ottokemi D 8505 17-DMAG ≥98% 5mg ₹5288674 2022-05-26 Buy

Properties

Melting point :>270°C (dec.)
Boiling point :810.5±65.0 °C(Predicted)
Density :1.20
storage temp. :Desiccate at -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :8.48±0.70(Predicted)
color :Very Dark Purple

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Geldanamycin is a potent inhibitor of Hsp90 that has poor water solubility. 17-DMAG is a water-soluble derivative of geldanamycin which potently inhibits Hsp90 (IC50 = 24 nM) and has excellent bioavailability and tissue distribution in animals. Like other Hsp90 inhibitors, 17-DMAG has diverse anti-tumor actions and has potential in treating certain types of cancer. This compound also suppresses inflammation by interfering with signaling through the NF-κB pathway. 17-DMAG also ameliorates high fat diet-induced renal failure in a mouse model of diabetes.

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Dimethyl sulfoxide Ethyl acrylate Ethyl propiolate Methyl sulfone 99-98-9 N,N-Dimethylacetamide 3-Dimethylaminopropylamine N,N-Dimethylformamide Etanol Ethyl acetate Ethyl cyanoacetate Ethylparaben Trinexapac-ethyl 17-DMAG Geldanamycin

Related product price

Suppliers and manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Alvespimycin
₹0.00 /25kg
Alvespimycin CAS:467214-20-6
career henan chemical co
Alvespimycin
₹1.00 /1KG
Alvespimycin CAS:467214-20-6
Otto Chemie Pvt. Ltd.
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
TargetMol Chemicals Inc.
Baoji Guokang Bio-Technology Co., Ltd.
BOC Sciences
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited