Andrographolide
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- ₹5607 - ₹26700
- Product name: Andrographolide
- CAS: 5508-58-7
- MF: C20H30O5
- MW: 350.45
- EINECS:226-852-5
- MDL Number:MFCD07778082
- Synonyms:Andrographolide/Andrographis Paniculata P.E.;5-alpha,6-alpha,8a-alpha))-t ;2(3h)-furanone,3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-met ;3-(2-(Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene- 1-naphthalenyl)ethylidene)dihydro-4-hydroxy-, (1R-(1-alpha(E(S*)),4a-beta,5- alpha,6-alpha,8a-alpha))-2(3H)-furanone;(3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-1,2,3,4,4a,5,6,7,8,8a-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenenaphthalene-1-yl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone;(S)-3-[(E)-2-[[(1R,4aα)-Decahydro-6β-hydroxy-5β-hydroxymethyl-5,8aβ-dimethyl-2-methylenenaphthalen]-1β-yl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone;Andrographolid;Andrographolide (50 mg)
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Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
- ottokemi
Package
- 5MG
- 50MG
- 100MG
- 500MG
- 1gm
- 1G
- 5gm
- 5G
- ManufacturerTCI Chemicals (India)
- Product numberA2459
- Product descriptionAndrographolide
- Packaging1G
- Price₹7700
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberA2459
- Product descriptionAndrographolide
- Packaging5G
- Price₹26700
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number365645
- Product descriptionAndrographolide 98%
- Packaging100MG
- Price₹6040.35
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number172060
- Product descriptionAndrographolide - CAS 5508-58-7 - Calbiochem A bicyclic diterpenoid lactone that displays anti-viral, anti-inflammatory, anti-apoptotic, and anti-hyperglycemic properties.
- Packaging50MG
- Price₹7070
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number90281
- Product descriptionAndrographolide analytical standard
- Packaging5MG
- Price₹10965.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number365645
- Product descriptionAndrographolide 98%
- Packaging500MG
- Price₹19950.48
- Updated2022-06-14
- Buy
- Manufacturerottokemi
- Product number A 2392
- Product descriptionAndrographolide 99%
- Packaging100mg
- Price₹5607
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number A 2394
- Product descriptionAndrographolide 98%
- Packaging1gm
- Price₹7605
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number A 2392
- Product descriptionAndrographolide 99%
- Packaging500mg
- Price₹18099
- Updated2022-05-26
- Buy
- Manufacturerottokemi
- Product number A 2394
- Product descriptionAndrographolide 98%
- Packaging5gm
- Price₹23409
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | A2459 | Andrographolide | 1G | ₹7700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | A2459 | Andrographolide | 5G | ₹26700 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | 365645 | Andrographolide 98% | 100MG | ₹6040.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 172060 | Andrographolide - CAS 5508-58-7 - Calbiochem A bicyclic diterpenoid lactone that displays anti-viral, anti-inflammatory, anti-apoptotic, and anti-hyperglycemic properties. | 50MG | ₹7070 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 90281 | Andrographolide analytical standard | 5MG | ₹10965.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 365645 | Andrographolide 98% | 500MG | ₹19950.48 | 2022-06-14 | Buy |
| ottokemi | A 2392 | Andrographolide 99% | 100mg | ₹5607 | 2022-05-26 | Buy |
| ottokemi | A 2394 | Andrographolide 98% | 1gm | ₹7605 | 2022-05-26 | Buy |
| ottokemi | A 2392 | Andrographolide 99% | 500mg | ₹18099 | 2022-05-26 | Buy |
| ottokemi | A 2394 | Andrographolide 98% | 5gm | ₹23409 | 2022-05-26 | Buy |
Properties
Melting point :229-232 °C (lit.)
Boiling point :557.3±50.0 °C(Predicted)
alpha :-126 º (c=1.5,HAc)
Density :d421 1.2317
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 8 mg/ml).
pka :12.36±0.20(Predicted)
form :Off-white solid
color :Off-white
optical activity :[α]20/D 126°, c = 1.5 in acetic acid
λmax :223nm(MeOH)(lit.)
Merck :14,633
BRN :42762
Stability :Stable for 2 years from date of purchsae as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :BOJKULTULYSRAS-QPSYGYIJSA-N
LogP :0.424 (est)
CAS DataBase Reference :5508-58-7
Boiling point :557.3±50.0 °C(Predicted)
alpha :-126 º (c=1.5,HAc)
Density :d421 1.2317
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 8 mg/ml).
pka :12.36±0.20(Predicted)
form :Off-white solid
color :Off-white
optical activity :[α]20/D 126°, c = 1.5 in acetic acid
λmax :223nm(MeOH)(lit.)
Merck :14,633
BRN :42762
Stability :Stable for 2 years from date of purchsae as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :BOJKULTULYSRAS-QPSYGYIJSA-N
LogP :0.424 (est)
CAS DataBase Reference :5508-58-7
Safety Information
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Description
Andrographolide is the bitter principle, a colorless and neutral crystalline substance. It is the major labdane diterpenoid isolated from Andrographis paniculate. It exhibits antiviral, anti-inflammatory, and anticancer activities. The underlying mechanism is the inhibition of the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling (specifically p38 MAPK/ERK1/2) pathway and downstream transcription factors such as nuclear factor kappa B (NF-κB) and nuclear factor of activated T cells (NFAT). Andrographolide is also confirmed with chemopreventive effects against and the inhibitory effects on cancer cell growth in breast, colon, epidermoid, gastric, liver, leukemia, myeloma, peripheral blood lymphocytes, and prostate cancers.Related product price
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