Argatroban
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- ₹0
- Product name: Argatroban
- CAS: 74863-84-6
- MF: C23H36N6O5S
- MW: 508.63
- EINECS:638-764-8
- MDL Number:MFCD23102419
- Synonyms:Argipidine;MQP;ARG025;MQPA;Argatroban;(2R,4R)-1-[5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acid;(2R)-1-[Nα-(3-Methyl-1,2,3,4-tetrahydroquinoline-8-ylsulfonyl)-L-arginyl]-4α-methylpiperidine-2β-carboxylic acid;(2R,4R)-1-[(2S)-5-Guanidino-2-(1,2,3,4-tetrahydro-3-methylquinolin-8-ylsulfonylamino)valeryl]-4-methylpiperidine-2-carboxylic acid
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
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Properties
Melting point :188-1890C
Boiling point :777.2±70.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :10.44±0.40(Predicted)
form :White to off-white powder.
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey :KXNPVXPOPUZYGB-IOVMHBDKSA-N
SMILES :N1(C(=O)[C@@H](NS(C2C3=C(C=CC=2)CC(C)CN3)(=O)=O)CCCNC(N)=N)CC[C@@H](C)C[C@@H]1C(O)=O
CAS DataBase Reference :74863-84-6(CAS DataBase Reference)
Boiling point :777.2±70.0 °C(Predicted)
Density :1.47±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml).
pka :10.44±0.40(Predicted)
form :White to off-white powder.
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey :KXNPVXPOPUZYGB-IOVMHBDKSA-N
SMILES :N1(C(=O)[C@@H](NS(C2C3=C(C=CC=2)CC(C)CN3)(=O)=O)CCCNC(N)=N)CC[C@@H](C)C[C@@H]1C(O)=O
CAS DataBase Reference :74863-84-6(CAS DataBase Reference)
Safety Information
Symbol(GHS): |
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Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
Argatroban is a reversible, competitive thrombin inhibitor (Ki = 5 nM) that shows selectivity for thrombin over other clotting pathway enzymes. It inhibits thrombin bound to fibrin clots as well as thrombin that is free in solution. This direct thrombin inhibitor prevents or alleviates thrombosis in cases of heparin-induced thrombocytopenia.More related product prices
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