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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Articaine hydrochloride

Articaine hydrochloride

Articaine hydrochloride Structure
  • ₹11009.03 - ₹15144.18
  • Product name: Articaine hydrochloride
  • CAS: 23964-57-0
  • MF: C13H20N2O3S.ClH
  • MW: 320.839
  • EINECS:245-957-7
  • MDL Number:MFCD00190157
  • Synonyms:methyl 4-methyl-3-[[(1-oxo-2-(propylamino)propyl]amino]-2-thenoate monohydrochloride ;CarticaineHCl;CARTICAINE HYDROCHLORIDE;Articaine hydrochloride;Methyl 4-methyl-3-(2-propylaminopropanoylamino)thiophene-2-carboxylate hydrochloride;Articaine Hydrochloride (125 mg);4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylic acid methyl ester hydrochloride;Methyl 4-methyl-3-[(N-propylalanyl)amino]-2-thiophenecarboxylate hydrochloride
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1093
  • Product descriptionArticaine hydrochloride ≥98% (HPLC)
  • Packaging50MG
  • Price₹11009.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1881
  • Product descriptionArticaine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹15144.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML1093 Articaine hydrochloride ≥98% (HPLC) 50MG ₹11009.03 2022-06-14 Buy
Sigma-Aldrich(India) PHR1881 Articaine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹15144.18 2022-06-14 Buy

Properties

Melting point :177-178°
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :H2O: soluble20mg/mL, clear
form :powder
color :white to beige
Stability :Hygroscopic
InChI :InChI=1S/C13H20N2O3S.ClH/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4;/h7,9,14H,5-6H2,1-4H3,(H,15,16);1H
InChIKey :GDWDBGSWGNEMGJ-UHFFFAOYSA-N
SMILES :C1(NC(=O)C(C)NCCC)C(C)=CSC=1C(=O)OC.Cl

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Articaine hydrochloride is a thiophene-containing local anesthetic pharmacologically similar to mepivacaine. Most local anesthetics act by abolishing voltage-gated sodium channel currents indiscriminately in all populations of neurons. Articaine is an amide local anesthetic most commonly used in dentistry. It possesses a unique ester side chain that is metabolized rapidly by circulating esterases. Articaine is reported to modify cardiac action potentials and ion currents only at concentrations higher than the therapeutic range needed to inhibit voltage-gated sodium channels.

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