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ChemicalBook > Product Catalogue >API >Specialty drugs >Dermatology drugs >Asiatic acid

Asiatic acid

Asiatic acid Structure
  • ₹4090 - ₹65469.6
  • Product name: Asiatic acid
  • CAS: 464-92-6
  • MF: C30H48O5
  • MW: 488.7
  • EINECS:482-720-9
  • MDL Number:MFCD00238541
  • Synonyms:(1s,2r,4as,6ar,6as,6br,8ar,9s,10s,11r,12as,14br)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1h-picene-4a-carboxylic acid;ASIATIC ACID;URS-12-EN-28-OIC ACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-;Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2.alpha.,3.beta.,4.alpha.)-;ASIATIC ACID(P);Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2α,3β,4α)-;ASIATICACID:URS-12-EN-28-OICACID, 2,3,23-TRIHYDROXY-, (2A,3B,4A)-,;2α,3β,23-Trihydroxyurs-12-en-28-oicacid
8 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ALFA India
  • SRL

Package

  • 10MG
  • 50MG
  • 200MG
  • 500MG
  • ManufacturerTCI Chemicals (India)
  • Product numberA2475
  • Product descriptionAsiatic Acid
  • Packaging200MG
  • Price₹13800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number546712
  • Product descriptionAsiatic acid 97%
  • Packaging500MG
  • Price₹17991.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA2612
  • Product descriptionAsiatic acid ≥98% (HPLC), from Centella asiatica
  • Packaging10MG
  • Price₹32117.78
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number89773
  • Product descriptionAsiatic acid analytical standard
  • Packaging10MG
  • Price₹32226.03
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberA2612
  • Product descriptionAsiatic acid ≥98% (HPLC), from Centella asiatica
  • Packaging50MG
  • Price₹65469.6
  • Updated2022-06-14
  • Buy
  • ManufacturerALFA India
  • Product numberALF-H60149-ME
  • Product descriptionAsiatic acid, 97%
  • Packaging500mg
  • Price₹51663
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number27999
  • Product descriptionAsiatic Acid pure, 97%
  • Packaging200mg
  • Price₹14370
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number27999
  • Product descriptionAsiatic Acid pure, 97%
  • Packaging50mg
  • Price₹4090
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2475 Asiatic Acid 200MG ₹13800 2022-05-26 Buy
Sigma-Aldrich(India) 546712 Asiatic acid 97% 500MG ₹17991.15 2022-06-14 Buy
Sigma-Aldrich(India) A2612 Asiatic acid ≥98% (HPLC), from Centella asiatica 10MG ₹32117.78 2022-06-14 Buy
Sigma-Aldrich(India) 89773 Asiatic acid analytical standard 10MG ₹32226.03 2022-06-14 Buy
Sigma-Aldrich(India) A2612 Asiatic acid ≥98% (HPLC), from Centella asiatica 50MG ₹65469.6 2022-06-14 Buy
ALFA India ALF-H60149-ME Asiatic acid, 97% 500mg ₹51663 2022-05-26 Buy
SRL 27999 Asiatic Acid pure, 97% 200mg ₹14370 2022-05-26 Buy
SRL 27999 Asiatic Acid pure, 97% 50mg ₹4090 2022-05-26 Buy

Properties

Melting point :325-330 °C(lit.)
Boiling point :609.4±55.0 °C(Predicted)
Density :1.18±0.1 g/cm3(Predicted)
RTECS :YU9580000
storage temp. :2-8°C
solubility :methanol: soluble1mg/mL, clear, colorless
pka :4.66±0.70(Predicted)
form :powder
color :white
Water Solubility :Soluble in dimethyl sulfoxide, ethanol and dimethylformamide. Sparingly soluble in water
InChIKey :JXSVIVRDWWRQRT-UYDOISQJSA-N
LogP :5.748 (est)
CAS DataBase Reference :464-92-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

Asiatic acid is a pentacyclic triterpene isolated from a variety of plants, including C. asiatica, used in traditional medicines. In addition to anti-inflammatory actions, asiatic acid stimulates wound healing by increasing collagen production. It has also been found to induce cell cycle arrest and apoptosis in breast cancer cells (IC50 = 5.9 μM for MCF-7 cells) and block angiogenesis in cells and tumors from glioblastomas. Asiatic acid also impacts amyloid-β precursor protein processing by down regulating BACE1 while increasing ADAM10 maturation in primary rat cortical neurons. In addition, it reduces neuronal damage and cognitive defects resulting from glutamate administration in vivo in mice while demonstrating protective effects against glutamate-induced apoptosis in isolated SH-SY5Y cells.

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