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ChemicalBook > Product Catalogue >Natural Products >Alkaloids >BANISTERINE MONOHYDRATE

BANISTERINE MONOHYDRATE

BANISTERINE MONOHYDRATE Structure
  • ₹6440.88 - ₹9600
  • Product name: BANISTERINE MONOHYDRATE
  • CAS: 442-51-3
  • MF: C13H12N2O
  • MW: 212.25
  • EINECS:207-131-4
  • MDL Number:MFCD00150055
  • Synonyms:Harmine;1-Methyl-7-Methoxy-β-carboline;Hal base;Harmine(Banisterine);1-Methyl-7-methoxy-beta-carboline;4-b)indole,7-methoxy-1-methyl-9h-pyrido( ;7-Methoxy-1-methyl-9H-beta-carboline;9H-Pyrido[3,4-b]indole, 7-methoxy-1-methyl-
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberH0001
  • Product descriptionHarmine
  • Packaging1G
  • Price₹9600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number286044
  • Product descriptionHarmine 98%
  • Packaging1G
  • Price₹6440.88
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) H0001 Harmine 1G ₹9600 2022-05-26 Buy
Sigma-Aldrich(India) 286044 Harmine 98% 1G ₹6440.88 2022-06-14 Buy

Properties

Melting point :262-264 °C(lit.)
Boiling point :352.09°C (rough estimate)
Density :1.1128 (rough estimate)
refractive index :1.6920 (estimate)
storage temp. :Sealed in dry,Room Temperature
solubility :Solubility Slightly soluble in water, ethanol, ether, chloroform
form :Crystalline Powder
pka :7.7(at 25℃)
color :White to off-white
PH Range :Blue 0 uorescence (7.2) to yellow 0 uorescence (8.9)
Water Solubility :Soluble in DMSO (100 mM), DMF (~1.5 mg/ml), ethanol (~1.5 mg/ml), and PBS (pH 7.2, ~0.25 mg/ml). Insoluble in water.
λmax :241nm, 301nm, 336nm
Merck :14,4616
BRN :178813
Major Application :Inks, antitumor agents, inhibition of cell proliferation, blocking breast and prostate cancer cells, tracer for ductal pancreatic cancer, DNA binding properties, treatment of neoplasia, antioxidants, therapy of depression, antileishmanial agent, treatment of parkinsonism, antiAIDS agents, antihypoxia agents, drugs, treatment of dependency disorder, psychiatric and neurological illness, antibiotics, antimalarial agents
InChIKey :BXNJHAXVSOCGBA-UHFFFAOYSA-N
LogP :3.560
CAS DataBase Reference :442-51-3(CAS DataBase Reference)
NIST Chemistry Reference :Harmine(442-51-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Harmine, inhibits the Wnt signaling pathway in a cell-specific manner. Down-regulates inflammatory gene expression (TNF-α, IL-1β, iNOS). Reversibly inhibits MAO-A (monoamine oxidase A) but has no effect on MAO-B. Harmine is an inhibitor of Dyrk1A, Dyrk2 and Dyrk3.

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