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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Antigout Drugs >Benzbromarone

Benzbromarone

Benzbromarone Structure
  • ₹3400 - ₹13600
  • Product name: Benzbromarone
  • CAS: 3562-84-3
  • MF: C17H12Br2O3
  • MW: 424.08
  • EINECS:222-630-7
  • MDL Number:MFCD00078962
  • Synonyms:LABOTEST-BB LT00134669;BENZBROMARONE;3-[3,5-DIBROMO-4-HYDROXYBENZOYL]-2-ETHYLBENZOFURAN;3,5-dibromo-4-hydroxyphenyl-2-ethylbenzo[b]furan-3-yl ketone;BENZBROMARONE, REFERENCE SPECTRUM EP STANDARD;BENZBROMARONE, MM(CRM STANDARD);(3,5-Dibromo-4-hydroxyphenyl)(2-ethylbenzofuran-3-yl)ketone;(3,5-Dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
4 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 50MG
  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberB4099
  • Product descriptionBenzbromarone min. 98.0 %
  • Packaging1G
  • Price₹3400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB4099
  • Product descriptionBenzbromarone min. 98.0 %
  • Packaging5G
  • Price₹13600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number09147
  • Product descriptionBenzbromarone certified reference material, TraceCERT?
  • Packaging50MG
  • Price₹8616.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB5774
  • Product descriptionBenzbromarone analytical standard
  • Packaging1G
  • Price₹8876.5
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B4099 Benzbromarone min. 98.0 % 1G ₹3400 2022-05-26 Buy
TCI Chemicals (India) B4099 Benzbromarone min. 98.0 % 5G ₹13600 2022-05-26 Buy
Sigma-Aldrich(India) 09147 Benzbromarone certified reference material, TraceCERT? 50MG ₹8616.7 2022-06-14 Buy
Sigma-Aldrich(India) B5774 Benzbromarone analytical standard 1G ₹8876.5 2022-06-14 Buy

Properties

Melting point :151°
Boiling point :514.1±50.0 °C(Predicted)
Density :1.6211 (rough estimate)
refractive index :1.6010 (estimate)
storage temp. :Inert atmosphere,2-8°C
solubility :Practically insoluble in water, freely soluble in acetone and in methylene chloride, sparingly soluble in ethanol (96 per cent).
pka :4.66±0.25(Predicted)
form :Solid
color :White to Light yellow
Merck :14,1065
InChIKey :WHQCHUCQKNIQEC-UHFFFAOYSA-N
CAS DataBase Reference :3562-84-3(CAS DataBase Reference)
EPA Substance Registry System :Methanone, (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-3-benzofuranyl)- (3562-84-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Benzbromarone is an inhibitor of the urate anion transporter (IC50 = 0.3 μM for hURAT1) that prevents renal urate resorption. It also potently inhibits CYP2C9 (Ki = 20 nM), a major cytochrome P450 enzyme involved in the metabolic clearance of a wide range of therapeutic agents. Several analogs of benzabromarone have been developed with varying binding affinities to CYP2C9 in order to study adverse drug-drug interactions.

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