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BIBF 1202

BIBF 1202 Structure
  • ₹0
  • Product name: BIBF 1202
  • CAS: 894783-71-2
  • MF: C30H31N5O4
  • MW: 525.6
  • EINECS:
  • MDL Number:MFCD28167767
  • Synonyms:(Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1 -yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid;Nintedanib impurity A;BIBF 1202;(3Z)-2,3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid;Intedanib Impurity A;Nintedanib Carboxylic Acid;Nintedanib-010;Nintedanib-1
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>216°C (dec.)
Boiling point :759.5±60.0 °C(Predicted)
Density :1.331±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Aqueous Base (Slightly, Heated)
pka :3.94±0.20(Predicted)
form :Solid
color :Light Yellow to Yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC50 value of 62 nM.

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Methyl oxindole-5-carboxylate P-ANISALDEHYDE DIMETHYL ACETAL 2-OXO-2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID (3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester 1912-30-7 4'-Amino-N-methylacetanilide 14719-83-6 ALPHA,ALPHA,2,4-TETRACHLOROTOLUENE N-Methyl-4-nitroaniline Methyl 2-oxindole-4-carboxylate 14192-26-8 Nintedanib 4-Chloro-3-nitrobenzoic acid 1,3,5-trichloro-2-(chloromethyl)benzene 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate METHYL OXINDOLE-7-CARBOXYLATE MES

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Suppliers and manufacturers

CLEARSYNTH LABS LTD. Pharmaffiliates Analytics and Synthetics P. Ltd SynZeal Research Pvt Ltd
BOC Sciences
InvivoChem
Nanjing Doge Biomedical Technology Co., Ltd
China National Standard Pharmaceutical Corporation Limited
LEAPCHEM CO., LTD.
Arizest(Shanghai)Pharmatech Co., Ltd
Amadis Chemical Company Limited