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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Sex Hormone Drugs >BUSERELIN

BUSERELIN

BUSERELIN Structure
  • ₹8703.3
  • Product name: BUSERELIN
  • CAS: 68630-75-1
  • MF: C62H90N16O15
  • MW: 1299.5
  • EINECS:636-185-5
  • MDL Number:MFCD01716229
  • Synonyms:6-(o-(1,1-dimethylethyl)-d-serine)-luteinizinghormone-releasingfactor(pig ;9-(n-ethyl-l-prolinamide)-10-deglycinamide,monoacetate(salt) ;buserelinacetate ;hoe766 ;hoe766mp ;PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHET;P-GLU-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHET;pGlu-His-Trp-Ser-Tyr-D-Ser(t-Bu)-Leu-Arg-Pro-NHEt, des-Gly10-[D-Ser[t-Bu]6]-LH-RH ethylamide
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberB3303
  • Product descriptionBuserelin acetate salt ≥90% (HPLC)
  • Packaging1MG
  • Price₹8703.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) B3303 Buserelin acetate salt ≥90% (HPLC) 1MG ₹8703.3 2022-06-14 Buy

Properties

Melting point :186-188°C
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form :Solid
color :White to Off-White
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Buserelin acetate is a potent analog of the hypothalamic hormone, luteinizing hormone-releasing hormone (LH-RH). Chronic administration of higher doses of buserelin desensitizes the pituitary, resulting in a decreased production of luteinizing hormone (LH), follicle stimulating hormone (FSH), and eventually sex steroids (testosterone in males and estradiol in females). Initial approval is for use in achieving medical castration in the treatment of advanced prostate cancer. It has also been investigated for the treatment of endometriosis, leiomyoma, precocious puberty, advanced breast cancer and infertility.

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