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ChemicalBook > Product Catalogue >API >Hormones and the Endocrine System >Sex Hormone Drugs >Bicalutamide

Bicalutamide

Bicalutamide Structure
  • ₹3500 - ₹50520.28
  • Product name: Bicalutamide
  • CAS: 90357-06-5
  • MF: C18H14F4N2O4S
  • MW: 430.37
  • EINECS:200-001-8
  • MDL Number:MFCD00869971
  • Synonyms:(+-)--2-hydroxy-2-methyl ;propanamide,n-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl) ;Bicalutamide (Subject to patent free);ICI-176334;BICALUTAMIDE;N-[(4-CYANO-3-TRIFLUOROMETHYL)PHENYL]-3-[(4-FLUOROPHENYL)SULFONYL]-2-HYDROXY-2-METHYLPROPANAMIDE;N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-3-[(4-FLUOROPHENYL)SULFONYL]-2-HYDROXY-2-METHYLPROPIONANILIDE;Bicalutamide&Int.
Price5 Properties Safety Information Description
5 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 200MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberB3206
  • Product descriptionBicalutamide
  • Packaging200MG
  • Price₹3500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3206
  • Product descriptionBicalutamide
  • Packaging1G
  • Price₹6200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1678
  • Product descriptionBicalutamide Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9926.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB9061
  • Product descriptionBicalutamide (CDX) ≥98% (HPLC), powder
  • Packaging10MG
  • Price₹12654.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB9061
  • Product descriptionBicalutamide (CDX) ≥98% (HPLC), powder
  • Packaging50MG
  • Price₹50520.28
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B3206 Bicalutamide 200MG ₹3500 2022-05-26 Buy
TCI Chemicals (India) B3206 Bicalutamide 1G ₹6200 2022-05-26 Buy
Sigma-Aldrich(India) PHR1678 Bicalutamide Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9926.53 2022-06-14 Buy
Sigma-Aldrich(India) B9061 Bicalutamide (CDX) ≥98% (HPLC), powder 10MG ₹12654.43 2022-06-14 Buy
Sigma-Aldrich(India) B9061 Bicalutamide (CDX) ≥98% (HPLC), powder 50MG ₹50520.28 2022-06-14 Buy

Properties

Melting point :191-193°C
Boiling point :650.3±55.0 °C(Predicted)
Density :1.52±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :11.49±0.29(Predicted)
form :powder
color :White to Off-White
λmax :270nm(CH3CN)(lit.)
Merck :14,1200
CAS DataBase Reference :90357-06-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P391 Collect spillage. Hazardous to the aquatic environment
P405 Store locked up.

Description

Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.

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Suppliers and manufacturers

AARTI INDUSTRIES LIMITED SGMR PHARMACEUTICALS PVT LTD Anant Pharmaceuticals Pvt Ltd USV Pvt Ltd Apotex Pharmachem India Pvt Ltd Cipla Ltd Vivimed Labs Ltd Aarti Industries Limited (AIL) Hetero Drugs Limited Sun Pharmaceutical Industries Ltd