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ChemicalBook > Product Catalogue >Natural Products >Terpenes >Baccatine III

Baccatine III

Baccatine III Structure
  • ₹15869.45
  • Product name: Baccatine III
  • CAS: 27548-93-2
  • MF: C31H38O11
  • MW: 586.63
  • EINECS:
  • MDL Number:MFCD00153921
  • Synonyms:BACCATINE III;(1S)-4α,10β-Bis(acetoxy)-2α-(benzoyloxy)-5β,20-epoxy-1,7β,13α-trihydroxytaxa-11-ene-9-one;(2aR)-6α,12bβ-Bisacetoxy-12β-(benzoyloxy)-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benzo[1,2-b]oxete-5-one;(2aR)-6α,12bβ-Diacetoxy-12β-benzoyloxy-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11α-methano-5H-cyclodeca[3,4]benzo[1,2-b]oxete-5-one;6α,12bβ-Diacetoxy-12β-benzoyloxy-1,2aβ,3,4,4a,6,9,10,11,12,12aβ,12b-dodecahydro-4α,9β,11β-trihydroxy-4aα,8,13,13-tetramethyl-7,11α-methano-5H-cyclodeca[3,4]benzo[1,2-b]oxete-5-one;Baccatine III,95%;baccatin Ⅲ;BACCATIN III 98%
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberB8154
  • Product descriptionBaccatin III ≥95% (HPLC)
  • Packaging5MG
  • Price₹15869.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) B8154 Baccatin III ≥95% (HPLC) 5MG ₹15869.45 2022-06-14 Buy

Properties

Melting point :229-234 °C
Boiling point :562.81°C (rough estimate)
Density :1.2062 (rough estimate)
refractive index :1.5455-1.5475
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO : 125 mg/mL (213.08 mM; Need ultrasonic)
pka :12.76±0.70(Predicted)
form :Solid
color :White to off-white
Water Solubility :insoluble
Stability :4 Year Shelf Life
CAS DataBase Reference :27548-93-2

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Baccatin III is the precursor to paclitaxel/ taxol. Antileukaemic and antitumor agent isolated from the bark of the Pacific yew tree (Taxus breviofolia). Baccatin III binds to tubules when they are assembled in the cell and stabilizes the polymerized form of tubules so that they remain assembled even under conditions in which microtubules dissociate into tubulin subunits. Baccatin III is also an inducer of apoptosis and shows antitumor properties in vitro

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Suppliers and manufacturers

GLP Pharma Standards Vishrudh laboratories pvt ltd CLEARSYNTH LABS LTD. A.J Chemicals Pharmaffiliates Analytics and Synthetics P. Ltd SynZeal Research Pvt Ltd Satyan Pharmaceuticals Pvt Ltd. Manus Aktteva Biopharma LLP Clearsynth Labs Sai Phytoceuticals Pvt., Ltd.