Paclitaxel
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- ₹549 - ₹168790.01
- Product name: Paclitaxel
- CAS: 33069-62-4
- MF: C47H51NO14
- MW: 853.92
- EINECS:608-826-9
- MDL Number:MFCD00869953
- Synonyms:N-BENZYL-BETA-PHENYLISOSERINE ESTER;PACLITAXEL, TAXUS BREVIFOLIA;PACLITAXEL, TAXUS SPECIES;PACLITAXOL;PACLITAXEL;TAXOL(TM);taxol a;TAXOL EQUIVALENT
25 prices
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- Sigma-Aldrich(India)
- TCI Chemicals (India)
- Sigma-Aldrich
- ottokemi
- SRL
Package
- 1MG
- 5MG
- 10mg
- 25MG
- 50mg
- 100MG
- 200MG
- 250mg
- ManufacturerSigma-Aldrich(India)
- Product numberT7191
- Product descriptionPaclitaxel from semisynthetic, ≥97%
- Packaging1MG
- Price₹5304.25
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT7402
- Product descriptionPaclitaxel from Taxus brevifolia, ≥95% (HPLC), powder
- Packaging1MG
- Price₹5358.38
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT1912
- Product descriptionPaclitaxel from Taxus yannanensis, powder
- Packaging1MG
- Price₹5585.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT7191
- Product descriptionPaclitaxel from semisynthetic, ≥97%
- Packaging5MG
- Price₹17265.88
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT7402
- Product descriptionPaclitaxel from Taxus brevifolia, ≥95% (HPLC), powder
- Packaging5MG
- Price₹17753
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT1912
- Product descriptionPaclitaxel from Taxus yannanensis, powder
- Packaging5MG
- Price₹18250.95
- Updated2022-06-14
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberP1632
- Product descriptionPaclitaxel
- Packaging100MG
- Price₹29600
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR1803
- Product descriptionPaclitaxel Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging200MG
- Price₹48647.55
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number580555
- Product descriptionPaclitaxel, Taxus sp. - CAS 33069-62-4 - Calbiochem Antitumor and antileukemic agent isolated from the bark of the yew tree.
- Packaging25MG
- Price₹52910
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT7191
- Product descriptionPaclitaxel from semisynthetic, ≥97%
- Packaging25MG
- Price₹53616.23
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT1912
- Product descriptionPaclitaxel from Taxus yannanensis, powder
- Packaging25MG
- Price₹60630.83
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberT7402
- Product descriptionPaclitaxel from Taxus brevifolia, ≥95% (HPLC), powder
- Packaging25MG
- Price₹62525.2
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number580555
- Product descriptionPaclitaxel, Taxus sp. - CAS 33069-62-4 - Calbiochem Antitumor and antileukemic agent isolated from the bark of the yew tree.
- Packaging100MG
- Price₹168790.01
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich
- Product number580556
- Product descriptionPaclitaxel, Semi-Synthetic - CAS 33069-62-4 - Calbiochem A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.
- Packaging5MG
- Price₹11730
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number580556
- Product descriptionPaclitaxel, Semi-Synthetic - CAS 33069-62-4 - Calbiochem A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants.
- Packaging5MG
- Price₹11730
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number580555
- Product descriptionPaclitaxel, Taxus sp. - CAS 33069-62-4 - Calbiochem Antitumor and antileukemic agent isolated from the bark of the yew tree.
- Packaging5MG
- Price₹13220
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | T7191 | Paclitaxel from semisynthetic, ≥97% | 1MG | ₹5304.25 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T7402 | Paclitaxel from Taxus brevifolia, ≥95% (HPLC), powder | 1MG | ₹5358.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T1912 | Paclitaxel from Taxus yannanensis, powder | 1MG | ₹5585.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T7191 | Paclitaxel from semisynthetic, ≥97% | 5MG | ₹17265.88 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T7402 | Paclitaxel from Taxus brevifolia, ≥95% (HPLC), powder | 5MG | ₹17753 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T1912 | Paclitaxel from Taxus yannanensis, powder | 5MG | ₹18250.95 | 2022-06-14 | Buy |
| TCI Chemicals (India) | P1632 | Paclitaxel | 100MG | ₹29600 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | PHR1803 | Paclitaxel Pharmaceutical Secondary Standard; Certified Reference Material | 200MG | ₹48647.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 580555 | Paclitaxel, Taxus sp. - CAS 33069-62-4 - Calbiochem Antitumor and antileukemic agent isolated from the bark of the yew tree. | 25MG | ₹52910 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T7191 | Paclitaxel from semisynthetic, ≥97% | 25MG | ₹53616.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T1912 | Paclitaxel from Taxus yannanensis, powder | 25MG | ₹60630.83 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | T7402 | Paclitaxel from Taxus brevifolia, ≥95% (HPLC), powder | 25MG | ₹62525.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 580555 | Paclitaxel, Taxus sp. - CAS 33069-62-4 - Calbiochem Antitumor and antileukemic agent isolated from the bark of the yew tree. | 100MG | ₹168790.01 | 2022-06-14 | Buy |
| Sigma-Aldrich | 580556 | Paclitaxel, Semi-Synthetic - CAS 33069-62-4 - Calbiochem A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants. | 5MG | ₹11730 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 580556 | Paclitaxel, Semi-Synthetic - CAS 33069-62-4 - Calbiochem A semi-synthetic form of Paclitaxel having no contamination by natural taxanes. Also has reduced levels of epimerization products as contaminants. | 5MG | ₹11730 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 580555 | Paclitaxel, Taxus sp. - CAS 33069-62-4 - Calbiochem Antitumor and antileukemic agent isolated from the bark of the yew tree. | 5MG | ₹13220 | 2022-06-14 | Buy |
Properties
Melting point :213 °C (dec.)(lit.)
Boiling point :774.66°C (rough estimate)
alpha :D20 -49° (methanol)
Density :0.200
refractive index :-49 ° (C=1, MeOH)
Flash point :9℃
storage temp. :2-8°C
solubility :methanol: 50 mg/mL, clear, colorless
form :powder
pka :11.90±0.20(Predicted)
color :white
Water Solubility :0.3mg/L(37 ºC)
λmax :227nm(MeOH)(lit.)
Merck :14,6982
BRN :1420457
Stability :Stable. Incompatible with strong oxidizing agents. Combustible.
InChIKey :RCINICONZNJXQF-MZXODVADSA-N
LogP :3.950 (est)
CAS DataBase Reference :33069-62-4(CAS DataBase Reference)
EPA Substance Registry System :Paclitaxel (33069-62-4)
Boiling point :774.66°C (rough estimate)
alpha :D20 -49° (methanol)
Density :0.200
refractive index :-49 ° (C=1, MeOH)
Flash point :9℃
storage temp. :2-8°C
solubility :methanol: 50 mg/mL, clear, colorless
form :powder
pka :11.90±0.20(Predicted)
color :white
Water Solubility :0.3mg/L(37 ºC)
λmax :227nm(MeOH)(lit.)
Merck :14,6982
BRN :1420457
Stability :Stable. Incompatible with strong oxidizing agents. Combustible.
InChIKey :RCINICONZNJXQF-MZXODVADSA-N
LogP :3.950 (est)
CAS DataBase Reference :33069-62-4(CAS DataBase Reference)
EPA Substance Registry System :Paclitaxel (33069-62-4)
Safety Information
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Description
Paclitaxel, a potent disruptor of microtubules derived from the bark of the Pacific yew tree, is widely used as a chemotherapeutic compound. Tested against a panel of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas, paclitaxel demonstrates IC50 values ranging from 2.5-7.5 nM. Paclitaxel disrupts multipolar spindle formation, inducing cell cycle arrest in various human cell cancer lines (IC50s = 6.7-18.5 nM) at both prophase and G1. It initiates apoptosis of cancer cells through multiple mechanisms involving p53-dependent and -independent pathways, Bcl-2 family members, cyclin-dependent kinases, and c-Jun N-terminal kinases/stress-activated protein kinases.More related product prices
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