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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Peripheral vasodilators >Betahistine

Betahistine

Betahistine Structure
  • ₹4150 - ₹21940
  • Product name: Betahistine
  • CAS: 5638-76-6
  • MF: C8H12N2
  • MW: 136.19
  • EINECS:227-086-4
  • MDL Number:MFCD00006362
  • Synonyms:N-Methyl-N-(2-pyridin-2-ylethyl)amine;METHYL-(2-PYRIDIN-2-YL-ETHYL)-AMINE;BETAHISTINE;AKOS BBS-00002883;2'-(2-N-METHYLAMINO ETHYL)PYRIDINE;2-(2-METHYLAMINOETHYL)PYRIDINE;2-[B-(METHYLAMINO)ETHYL]PYRIDINE;2-(METHYLAMINOETHYL)PYRIDINE
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5G
  • 25G
  • ManufacturerSigma-Aldrich(India)
  • Product numberM28804
  • Product description2-(2-Methylaminoethyl)pyridine 97%
  • Packaging5G
  • Price₹4150
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM28804
  • Product description2-(2-Methylaminoethyl)pyridine 97%
  • Packaging25G
  • Price₹21940
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M28804 2-(2-Methylaminoethyl)pyridine 97% 5G ₹4150 2022-06-14 Buy
Sigma-Aldrich(India) M28804 2-(2-Methylaminoethyl)pyridine 97% 25G ₹21940 2022-06-14 Buy

Properties

Boiling point :113-114 °C30 mm Hg(lit.)
Density :0.984 g/mL at 25 °C(lit.)
vapor pressure :17.7Pa at 25℃
refractive index :n20/D 1.518(lit.)
Flash point :206 °F
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :Chloroform (Slightly), DMSO (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Oil
pka :pKa 3.46 (Uncertain)
color :Light Yellow to Yellow
Water Solubility :1000g/L at 25℃
Merck :13,1181
LogP :0.68
CAS DataBase Reference :5638-76-6(CAS DataBase Reference)
EPA Substance Registry System :2-Pyridineethanamine, N-methyl- (5638-76-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Betahistine is a strong affinity histamine H3 receptor antagonist and weak affinity agonist of histamine H1 receptors.It belongs to a group of medicines known as histamine analogues. It works by improving blood flow in the inner ear, which reduces the build up of pressure. It is this pressure in the inner ear which is thought to cause nausea, vertigo (dizziness), tinnitus (ringing in the ears) and hearing loss suffered by people with Meniere’s disease. Betahistine is used in the treatment of these symptoms.

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