Betahistine dihydrochloride
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- ₹7166.15 - ₹17947.85
- Product name: Betahistine dihydrochloride
- CAS: 5579-84-0
- MF: C8H14Cl2N2
- MW: 209.12
- EINECS:226-966-5
- MDL Number:MFCD00012813
- Synonyms:BetahistineHCl ;n-methyl-2-pyridineethanamindihydrochloride ;METHYL(2-[2-PYRIDYL]ETHYL)AMINE;METHYL[2-(2-PYRIDYL)ETHYL]AMINE DIHYDROCHLORIDE;BETA-HISTINE DIHDROCHLORIDE;BETAHISTINE DIHYDROCHLORIDE;BETAHISTINE DIHYDROCHLORIDE BP (BATCH NO: BTI/20050715) ... AS PER INVOICE....;2-(2-(METHYLAMINO)ETHYL)PYRIDINE DIHYDROCHLORIDE
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 500MG
- 5G
- ManufacturerSigma-Aldrich(India)
- Product numberB4638
- Product descriptionBetahistine dihydrochloride ≥98%
- Packaging5G
- Price₹7166.15
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberPHR2097
- Product descriptionBetahistine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging500MG
- Price₹17947.85
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | B4638 | Betahistine dihydrochloride ≥98% | 5G | ₹7166.15 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR2097 | Betahistine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 500MG | ₹17947.85 | 2022-06-14 | Buy |
Properties
Melting point :150-154 °C
storage temp. :2-8°C
solubility :Very soluble in water, soluble in ethanol (96 per cent), practically insoluble in 2propanol.
form :powder
color :Pale Yellow
Stability :Hygroscopic
InChI :InChI=1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H
InChIKey :XVDFMHARQUBJRE-UHFFFAOYSA-N
SMILES :C1(CCNC)=NC=CC=C1.Cl.Cl
CAS DataBase Reference :5579-84-0(CAS DataBase Reference)
storage temp. :2-8°C
solubility :Very soluble in water, soluble in ethanol (96 per cent), practically insoluble in 2propanol.
form :powder
color :Pale Yellow
Stability :Hygroscopic
InChI :InChI=1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H
InChIKey :XVDFMHARQUBJRE-UHFFFAOYSA-N
SMILES :C1(CCNC)=NC=CC=C1.Cl.Cl
CAS DataBase Reference :5579-84-0(CAS DataBase Reference)
Safety Information
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Description
Betahistine dihydrochloride (BH.2HCl) is an orally active histamine analog which has been used to control vertigo, lack of hearing and tinnitus related to Ménière’s disease. The mechanism of BH.2HCl is to reduce the pressure of the membranous labyrinth that results in enhancement of the microvasculature circulation and improves the signs of Ménière’s disease. Peroral administration undergoes extensive first-pass metabolism and gastric irritation in patients with peptic ulcer. In treatment of vertigo, a uniform and constant supply of drug is required in order to maintain steady-state concentration of the drug in the body. Unfortunately, BH.2HCl possesses a short half-life of about 3–4 h and requires frequent administration of the drug,12–15 thereby making it an ideal candidate for controlled release preparations.More related product prices
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