Bexarotene
- ₹9482.7 - ₹38417.93
- Product name: Bexarotene
- CAS: 153559-49-0
- MF: C24H28O2
- MW: 348.48
- EINECS:
- MDL Number:MFCD00932428
- Synonyms:LG 69;RO 26-4455;SR 11247;Targret;Bexarotene(4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentaMethyl-2-naphthalenyl)ethenyl]benzoic acid;Bexarotene, Free;Bexzarotene;Bexarotene - CAS 153559-49-0 - Calbiochem
4 prices
Selected condition:
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 10MG
- 50MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberB4798
- Product descriptionBexarotene
- Packaging100MG
- Price₹14500
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0282
- Product descriptionBexarotene ≥98% (HPLC)
- Packaging10MG
- Price₹9482.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number200499
- Product descriptionBexarotene - CAS 153559-49-0 - Calbiochem A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce Aβ40 and Aβ42 levels in APP/PS1 mice in an ApoE-depen
- Packaging50MG
- Price₹13870
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML0282
- Product descriptionBexarotene ≥98% (HPLC)
- Packaging50MG
- Price₹38417.93
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
TCI Chemicals (India) | B4798 | Bexarotene | 100MG | ₹14500 | 2022-05-26 | Buy |
Sigma-Aldrich(India) | SML0282 | Bexarotene ≥98% (HPLC) | 10MG | ₹9482.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 200499 | Bexarotene - CAS 153559-49-0 - Calbiochem A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce Aβ40 and Aβ42 levels in APP/PS1 mice in an ApoE-depen | 50MG | ₹13870 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML0282 | Bexarotene ≥98% (HPLC) | 50MG | ₹38417.93 | 2022-06-14 | Buy |
Properties
Melting point :230-231°C
Boiling point :489.7±44.0 °C(Predicted)
Density :1.042
RTECS :DH6834830
storage temp. :-20°C
solubility :Soluble in DMSO and ethanol
form :White powder
pka :4.08±0.10(Predicted)
color :white to beige
λmax :264nm(MeOH)(lit.)
Merck :14,1194
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
InChIKey :NAVMQTYZDKMPEU-UHFFFAOYSA-N
Boiling point :489.7±44.0 °C(Predicted)
Density :1.042
RTECS :DH6834830
storage temp. :-20°C
solubility :Soluble in DMSO and ethanol
form :White powder
pka :4.08±0.10(Predicted)
color :white to beige
λmax :264nm(MeOH)(lit.)
Merck :14,1194
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 week.
InChIKey :NAVMQTYZDKMPEU-UHFFFAOYSA-N
Safety Information
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Description
Bexarotene is a high-affinity ligand for retinoid X receptors (RXRs) (EC50 = 28, 25, and 20 nM for RXRα, β, and γ, respectively). It inhibits cell cycle progression, induces apoptosis, prevents or overcomes multidrug resistance through multidrug resistance protein 1 (MDR1), and blocks angiogenesis and metastasis, making it a promising chemopreventive agent against cancer. Bexarotene also, through RXR activation, stimulates clearance of soluble β-amyloid, reduces plaque area, and reverses deficits related to Alzheimer’s disease in mice.More related product prices
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