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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Antibiotics anticancer drugs >Bleomycin sulfate

Bleomycin sulfate

Bleomycin sulfate Structure
  • ₹6340 - ₹131025.8
  • Product name: Bleomycin sulfate
  • CAS: 9041-93-4
  • MF: C110H168N34O46S7
  • MW: 2927.17
  • EINECS:232-925-2
  • MDL Number:MFCD00070310
  • Synonyms:Bleomycin sulfate, 1.5-2.0 units/mg;BLEOMYCIN SULFATE, BPC;BLEOMYCIN SULFATE FROM STREPTOMYCES VERT ICILLUS, LYOPH.;BLEOMYCIN SULFATE FROM STREPTOMYCES VERTICILLUS 0 TO 5 °C;Blocamicina;BLEMOYCIN SULFATE;3-[[2-[2-[2-[2-[4-[2-[6-Amino-2-[1-(2-amino-2-carbamoyl-ethyl)amino-2-carbamoyl-ethyl]-5-methyl-pyrimidin-4-yl]carbonylamino-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(3H-imidazol-4-yl)propanoyl]amino-3-hydroxy-2-methyl-pentanoyl]amino-3-hydroxy-butanoyl]aminoethyl]-1,3-thiazol-4-yl]-1,3-thiazol-4-yl]carbonylamino]propyl-dimethyl-sulfonium hydrogen sulfate;Bleomycin Sulfate, Blenoxane
9 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL

Package

  • 1MG
  • 10MG
  • 20MG
  • 50MG
  • 15UNITS
  • ManufacturerTCI Chemicals (India)
  • Product numberB3972
  • Product descriptionBleomycin Sulfate (mixture)
  • Packaging10MG
  • Price₹10600
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3972
  • Product descriptionBleomycin Sulfate (mixture)
  • Packaging50MG
  • Price₹33200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number15361
  • Product descriptionBleomycin sulfate from Streptomyces verticillus for fluorescence, mixture of bleomycin sulfate salts, lyophilized, powder or crystals, white to off-white
  • Packaging1MG
  • Price₹18196.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number15361
  • Product descriptionBleomycin sulfate from Streptomyces verticillus for fluorescence, mixture of bleomycin sulfate salts, lyophilized, powder or crystals, white to off-white
  • Packaging10MG
  • Price₹83872.1
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB5507
  • Product descriptionBleomycin sulfate from Streptomyces verticillus crystalline, 1.5-2.0?U/mg
  • Packaging15UNITS
  • Price₹92488.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB8416
  • Product descriptionBleomycin sulfate from Streptomyces verticillus 1.5-2.0?units/mg solid, BioReagent, suitable for cell culture
  • Packaging15UNITS
  • Price₹112774.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB2434
  • Product descriptionBleomycin sulfate from Streptomyces verticillus BioXtra, crystalline
  • Packaging20MG
  • Price₹131025.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number20899
  • Product descriptionBleomycin Sulfate (BLM-S), 90%
  • Packaging10mg
  • Price₹6340
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number20899
  • Product descriptionBleomycin Sulfate (BLM-S), 90%
  • Packaging50mg
  • Price₹27330
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B3972 Bleomycin Sulfate (mixture) 10MG ₹10600 2022-05-26 Buy
TCI Chemicals (India) B3972 Bleomycin Sulfate (mixture) 50MG ₹33200 2022-05-26 Buy
Sigma-Aldrich(India) 15361 Bleomycin sulfate from Streptomyces verticillus for fluorescence, mixture of bleomycin sulfate salts, lyophilized, powder or crystals, white to off-white 1MG ₹18196.83 2022-06-14 Buy
Sigma-Aldrich(India) 15361 Bleomycin sulfate from Streptomyces verticillus for fluorescence, mixture of bleomycin sulfate salts, lyophilized, powder or crystals, white to off-white 10MG ₹83872.1 2022-06-14 Buy
Sigma-Aldrich(India) B5507 Bleomycin sulfate from Streptomyces verticillus crystalline, 1.5-2.0?U/mg 15UNITS ₹92488.8 2022-06-14 Buy
Sigma-Aldrich(India) B8416 Bleomycin sulfate from Streptomyces verticillus 1.5-2.0?units/mg solid, BioReagent, suitable for cell culture 15UNITS ₹112774.85 2022-06-14 Buy
Sigma-Aldrich(India) B2434 Bleomycin sulfate from Streptomyces verticillus BioXtra, crystalline 20MG ₹131025.8 2022-06-14 Buy
SRL 20899 Bleomycin Sulfate (BLM-S), 90% 10mg ₹6340 2022-05-26 Buy
SRL 20899 Bleomycin Sulfate (BLM-S), 90% 50mg ₹27330 2022-05-26 Buy

Properties

Melting point :200-204°C (dec.)
storage temp. :2-8°C
solubility :H2O: 20 mg/mL
form :powder
color :white
Water Solubility :Soluble in water or DMSO
Merck :14,1318
Stability :Stable for 1 year from the date of purchase. Solutions in distilled water may be stored at -20°C for up to 3 months.
InChIKey :OOXTWFJZZAJGKA-YWZNXBAZNA-N
CAS DataBase Reference :9041-93-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Bleomycin is a glycopeptide antitumor antibiotic produced by the bacterium S. verticillus. Its mechanism of action causes single- and double-strand DNA breaks in tumor cells, which interrupts the cell cycle. Bleomycin is thought to achieve this by chelating metal ions, producing a pseudoenzyme that reacts with oxygen to produce superoxide and hydroxide free radicals that cleave DNA. Bleomycin has been used for the treatment of Hodgkin’s lymphoma in combination with doxorubicin, squamous cell carcinomas, testicular cancer, as well as in animal models of pulmonary fibrosis.

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