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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Alkylating antineoplastic >Busulfan

Busulfan

Busulfan Structure
  • ₹4800 - ₹28608.3
  • Product name: Busulfan
  • CAS: 55-98-1
  • MF: C6H14O6S2
  • MW: 246.3
  • EINECS:200-250-2
  • MDL Number:MFCD00007562
  • Synonyms:BUSULFAN;tetramethylene bis(methanesulfonate);1,4-dimethanesulfonoxybutane;1,4-Bis(methyl sulfonoxy)butane;1,4-Butanediol dimethyl sulfonate;(1,4-bis(methanesulfonyloxy)butane) ;1,4-bis(methanesulfonoxy)butane ;1,4-Bis(methane-sulponyloxy)butane
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1ML
  • 10G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberB1022
  • Product description1,4-Butanediol Dimethanesulfonate
  • Packaging25G
  • Price₹4800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB2635
  • Product descriptionBusulfan analytical standard, for drug analysis
  • Packaging10G
  • Price₹5001.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB2635
  • Product descriptionBusulfan analytical standard, for drug analysis
  • Packaging25G
  • Price₹7945.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB-094
  • Product descriptionBusulfan solution 1?mg/mL in acetonitrile, certified reference material, ampule of 1?mL, Cerilliant?
  • Packaging1ML
  • Price₹28608.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B1022 1,4-Butanediol Dimethanesulfonate 25G ₹4800 2022-05-26 Buy
Sigma-Aldrich(India) B2635 Busulfan analytical standard, for drug analysis 10G ₹5001.15 2022-06-14 Buy
Sigma-Aldrich(India) B2635 Busulfan analytical standard, for drug analysis 25G ₹7945.55 2022-06-14 Buy
Sigma-Aldrich(India) B-094 Busulfan solution 1?mg/mL in acetonitrile, certified reference material, ampule of 1?mL, Cerilliant? 1ML ₹28608.3 2022-06-14 Buy

Properties

Melting point :114-117 °C(lit.)
Boiling point :359.3°C (rough estimate)
Density :1.305 (estimate)
refractive index :1.5630 (estimate)
Flash point :9℃
storage temp. :Inert atmosphere,Room Temperature
solubility :Very slightly soluble in water, freely soluble in acetone and in acetonitrile, very slightly soluble in ethanol (96 per cent).
form :Crystalline Powder
color :Pale Brown
Water Solubility :Decomposes
Merck :14,1505
BRN :1791786
Stability :Moisture Sensitive
CAS DataBase Reference :55-98-1(CAS DataBase Reference)
IARC :1 (Vol. 4, Sup 7, 100A) 2012
EPA Substance Registry System :Busulfan (55-98-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.

Description

Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent. It forms both intra- and interstrand crosslinks on DNA. In mammals, busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.

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