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C8 CERAMIDE

C8 CERAMIDE Structure
  • ₹0
  • Product name: C8 CERAMIDE
  • CAS: 74713-59-0
  • MF: C26H51NO3
  • MW: 425.69
  • EINECS:
  • MDL Number:MFCD00236496
  • Synonyms:N-OCTANOYLSPHINGOSINE, D-ERYTHRO;N-OCTANOYL-D-ERYTHRO-SPHINGOSINE;N-OCTANOYL-D-SPHINGOSINE;N-OCTANOYLSPHINGOSINE;D-erythro-N-Octanoylsphingosine;N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]Octanamide;N-Octanoyl-C18-sphingosine;N-Octanoyl-D-erythr
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :68-70°C
Boiling point :541.37°C (rough estimate)
Density :0.9974 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :−20°C
solubility :DMSO or ethanol: soluble
form :waxy solid
color :White
Stability :Temperature Sensitive
CAS DataBase Reference :74713-59-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

C-8 ceramide is a cell-permeable analog of naturally occurring ceramides. Unlike C-2 ceramide, it is metabolized within cells to generate natural ceramides, often causing a dramatic increase in cellular ceramide levels. For this reason, treatment of cells with C-8 ceramide may more closely mimic the effects of ceramide elevation than does treatment with shorter chain ceramide analogs. C-8 ceramide likely mediates many diverse biological activities, as do natural ceramides. It promotes the differentiation of human keratinocytes and induces apoptosis of both human leukemia cells and the U937 cell line.

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