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CALCEIN-AM

CALCEIN-AM Structure
  • ₹22569.99 - ₹187272.5
  • Product name: CALCEIN-AM
  • CAS: 148504-34-1
  • MF: C46H46N2O23
  • MW: 994.86
  • EINECS:200-664-3
  • MDL Number:MFCD28355895
  • Synonyms:3',6'-Di(O-acetyl)-2',7'-bis[N,N-bis(carboxymethyl)aminomethyl]fluoresceintetraacetoxymethylester,DMSOsolution;Calcein AM solution;CALCEIN, AM;CAL-AM;4',5'-Bis(N,N-bis(carboxymethyl)aminomethyl)fluorescein acetoxymethyl ester;Glycine, N,N'-((3',6'-bis(acetyloxy)-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-2',7'-diyl)bis(methylene))bis(N-(2-((acetyloxy)methoxy)-2-oxoethyl)-, bis((acetyloxy)methyl) ester;Calcein AcetoxyMethyl Ester;N,N'-[[3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(Methylene)]bis[N-[2-[(acetyloxy)Methoxy]-2-oxoethyl]glycine 1,1'-Bis[(acetyloxy) Methyl] Ester;NSC 689290
5 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 20X50μG
  • 5MG
  • 1MG
  • 100μL
  • ManufacturerSigma-Aldrich(India)
  • Product number206700
  • Product descriptionCalcein-AM - CAS 148504-34-1 - Calbiochem A cell-permeable, non-fluorescent, and hydrophobic compound, which is rapidly hydrolyzed by intracellular esterases releasing the membrane-impermeable
  • Packaging1MG
  • Price₹22569.99
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC1359
  • Product descriptionCalcein AM solution 4?mM in DMSO, ≥90% (HPLC), solution
  • Packaging100μL
  • Price₹32239.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number17783
  • Product descriptionCalcein-AM BioReagent, suitable for fluorescence, ≥95.0% (HPLC)
  • Packaging1MG
  • Price₹54254.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number56496
  • Product descriptionCalcein-AM Small Package (20 X 50 μg ), ≥95.0% (HPLC)
  • Packaging20X50μG
  • Price₹61594.25
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number17783
  • Product descriptionCalcein-AM BioReagent, suitable for fluorescence, ≥95.0% (HPLC)
  • Packaging5MG
  • Price₹187272.5
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 206700 Calcein-AM - CAS 148504-34-1 - Calbiochem A cell-permeable, non-fluorescent, and hydrophobic compound, which is rapidly hydrolyzed by intracellular esterases releasing the membrane-impermeable 1MG ₹22569.99 2022-06-14 Buy
Sigma-Aldrich(India) C1359 Calcein AM solution 4?mM in DMSO, ≥90% (HPLC), solution 100μL ₹32239.2 2022-06-14 Buy
Sigma-Aldrich(India) 17783 Calcein-AM BioReagent, suitable for fluorescence, ≥95.0% (HPLC) 1MG ₹54254.9 2022-06-14 Buy
Sigma-Aldrich(India) 56496 Calcein-AM Small Package (20 X 50 μg ), ≥95.0% (HPLC) 20X50μG ₹61594.25 2022-06-14 Buy
Sigma-Aldrich(India) 17783 Calcein-AM BioReagent, suitable for fluorescence, ≥95.0% (HPLC) 5MG ₹187272.5 2022-06-14 Buy

Properties

Melting point :>250℃
Boiling point :982.7±65.0 °C(Predicted)
Density :1.49±0.1 g/cm3(Predicted)
refractive index :n20/D 1.479
Flash point :85 °C
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL, clear, colorless to slightly yellow
pka :2.66±0.50(Predicted)
form :powder
color :Colorless
λmax :< 300 nm
Biological Applications :Calcium indicators; zinc indicators; cytotoxicity assays; apoptosis assays; viability assays; labile iron pool assays; chemotaxis probes; cell adhesion probes; mitochondrial probes; P-glycoprotein probes;multi-drug resistance probes;treating atherosclerosis,cancer;ischemic disease

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Calcein AM is a cell-permeable dye that, upon entering live cells, is cleaved by intracellular esterases, leaving membrane-impermeant calcein , a fluorescent indicator with absorption and emission maxima of 494 and 517 nm, respectively. It can be used as an indicator of cell viability, cell-cell communication, cytotoxicity, or changes in intracellular calcium, fluoride, iron, or mercury. As calcein is a substrate for multidrug resistance-associated protein 1 (MRP1) and multidrug resistance protein 3 (MDR3, P-glycoprotein 3), calcein AM is used to study these proteins and their regulation.

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