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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >CAPTOPRIL DISULFIDE

CAPTOPRIL DISULFIDE

CAPTOPRIL DISULFIDE Structure
  • ₹0
  • Product name: CAPTOPRIL DISULFIDE
  • CAS: 64806-05-9
  • MF: C18H28N2O6S2
  • MW: 432.55
  • EINECS:
  • MDL Number:MFCD08063643
  • Synonyms:CAPTOPRIL DISULFIDE;CAPTOPRIL DISULFIDE USP;CAPTOPRIL DISULFIDE USP(CRM STANDARD);CAPTOPRIL DISULFIDE WHO(CRM STANDARD);CAPTOPRIL DISULPHIDE BP STANDARD;Captopril Impurity A;Captopril Impurity G;Captopril Impurity J
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :224-226°C
Boiling point :714.8±60.0 °C(Predicted)
Density :1.383±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form :Solid
pka :3.29±0.20(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Captopril Disulfide is a reversible and competitive inhibitor of LTA4 hydrolase (IC50=11 M). Captopril has been shown to be an of angiotensin converting enzyme-1 (ACE1), but not ACE2(IC50 = 22 nM). Captopril demonstrates irreversible noncompetitive and competitive inhibitor of tyrosinase monophenolase and diphenolase activities, respectively. Captopril has also been shown to inhibit the formation of angiotensin II, a bioactive peptide that stimulates angiogenesis and increases microvessel density.

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