CARIPORIDE
- ₹8530.1 - ₹34445.15
- Product name: CARIPORIDE
- CAS: 159138-80-4
- MF: C12H17N3O3S
- MW: 283.35
- EINECS:1592732-453-0
- MDL Number:MFCD00864683
- Synonyms:CARIPORIDE;N-(diaminomethylene)-4-isopropyl-3-mesyl-benzamide;N-[bis(azanyl)methylidene]-3-methylsulfonyl-4-propan-2-yl-benzamide;N-(Aminoiminomethyl)-4-(1-methylethyl)-3-(methylsulfonyl)benzamide;BenzaMide,N-(aMinoiMinoMethyl)-4-(1-Methylethyl)-3-(Methylsulfonyl)-;Cariporide (HOE-642);CS-1692;Sodium/hydrogen Exchanger,Na+/H+ Exchanger (NHE),inhibit,Sodium-hydrogen Exchanger,HOE642,Inhibitor,Cariporide,HOE 642
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberSML1360
- Product descriptionCariporide ≥98% (HPLC)
- Packaging5MG
- Price₹8530.1
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberSML1360
- Product descriptionCariporide ≥98% (HPLC)
- Packaging25MG
- Price₹34445.15
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SML1360 | Cariporide ≥98% (HPLC) | 5MG | ₹8530.1 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | SML1360 | Cariporide ≥98% (HPLC) | 25MG | ₹34445.15 | 2022-06-14 | Buy |
Properties
Melting point :90-94° (dec)
Density :1.34
storage temp. :2-8°C
solubility :insoluble in H2O; ≥12.05 mg/mL in DMSO; ≥2.675 mg/mL in EtOH with gentle warming and ultrasonic
form :powder
color :white to beige
Density :1.34
storage temp. :2-8°C
solubility :insoluble in H2O; ≥12.05 mg/mL in DMSO; ≥2.675 mg/mL in EtOH with gentle warming and ultrasonic
form :powder
color :white to beige
Safety Information
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Description
The sodium-hydrogen exchanger isoform-1 (NHE-1) is the predominant isoform of the Na+/H+ exchanger and is expressed in the heart where it contributes to cardiomyocyte pH homeostasis. It plays an important role in the myocardial response to ischemia-reperfusion. Cariporide is a benzoylguanidine compound that inhibits NHE-1 with IC50 values ranging from 0.03-3.4 μM. It displays selectivity for NHE-1 over NHE-2, NHE-3, and NHE-5 (IC50s = 4.3-62, 1->100, and >30 μM, respectively). The cardioprotective efficacy of cariporide has been examined in clinical investigations of patients at risk for myocardial infarction.More related product prices
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₹8530.1-34445.15