CASTANOSPERMINE
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- ₹5880 - ₹10164.68
- Product name: CASTANOSPERMINE
- CAS: 79831-76-8
- MF: C8H15NO4
- MW: 189.21
- EINECS:
- MDL Number:MFCD00017555
- Synonyms:1,6,7,8-indolizinetetrol,octahydro-,(1s-(1-alpha,6-beta,7-alpha,8-beta,8a-bet ;7,8-indolizinetetrol,octahydro-,(1s,6s,7r,8r,8ar)-6 ;octahydro-1,6,7,8-indolizinetetrol(1s-(1-alpha,6-beta,7-alpha,8-beta,8a-beta ;CASTANOSPERMINE;CASTANOSPERMINE, CASTANOSPERMUM AUSTRALE;[1S-(1A,6B,7A,8B,8A-BETA)]-OCTAHYDRO-1,6,7,8-INDOLIZINETETROL;(1S,6S,7R,8AR)-TETRAHYDROXYOCTAHYDROINDOLIZINE;(1S,6S,7R,8R,8AR)-1,6,7,8-TETRAHYDROXYINDOLIZIDINE
2 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- 100MG
- ManufacturerSigma-Aldrich(India)
- Product number218775
- Product descriptionCastanospermine, Castanospermum australe - CAS 79831-76-8 - Calbiochem Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins.
- Packaging1MG
- Price₹5880
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number532673
- Product description(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine 98%
- Packaging100MG
- Price₹10164.68
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 218775 | Castanospermine, Castanospermum australe - CAS 79831-76-8 - Calbiochem Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins. | 1MG | ₹5880 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 532673 | (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine 98% | 100MG | ₹10164.68 | 2022-06-14 | Buy |
Properties
Melting point :213-217 °C (lit.)
alpha :D25 +79.7° (c = 0.93 in water)
Boiling point :421.9±45.0 °C(Predicted)
Density :1.53±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :1 M HCl: 20 mg/mL, clear, very faintly yellow
form :White solid
pka :6.09(at 25℃)
color :White or off-white
optical activity :[α]20/D +80°, c = 0.9 in H2O
Water Solubility :Soluble in water
Merck :13,1906
BRN :3588654
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :79831-76-8(CAS DataBase Reference)
alpha :D25 +79.7° (c = 0.93 in water)
Boiling point :421.9±45.0 °C(Predicted)
Density :1.53±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :1 M HCl: 20 mg/mL, clear, very faintly yellow
form :White solid
pka :6.09(at 25℃)
color :White or off-white
optical activity :[α]20/D +80°, c = 0.9 in H2O
Water Solubility :Soluble in water
Merck :13,1906
BRN :3588654
Stability :Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20°C for up to 3 months.
CAS DataBase Reference :79831-76-8(CAS DataBase Reference)
Safety Information
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Description
Glucosidases catalyze the cleavage of individual glucosyl residues from various glycoconjugates, including complex carbohydrates and glycoproteins. Castanospermine is an inhibitor of both α- and β-glucosidases, inhibiting lysosomal and neutral α-glucosidases with Ki values of 0.1 and 10 μM, respectively, and lysosomal and cytosolic β-glucosidases with Ki values of 7 and 40 μM, respectively. It is effective both in vitro and in vivo. Through its effects on glucosidases, castanospermine blocks N-linked glycosylation during post-translational modification of proteins, affecting protein trafficking and cell functions that are dependent on glycosylation, including angiogenesis. Castanospermine also interferes with viral replication and infection that is dependent on glucosidase activity.Related product price
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