CHARYBDOTOXIN

₹54384.8
Product name: CHARYBDOTOXIN
CAS: 95751-30-7
MF: C176H277N57O55S7
MW: 4295.89
EINECS:
MDL Number:MFCD00146378
Synonyms:CHARYBDOTOXIN;CHARYBDOTOXIN, RECOMBINANT;CHARYBDOTOXIN, RECOMBINANT, E COLI;CHARYBDOTOXIN, LEIURUS QUINQUESTRIATUS HEBRAEUS;CHTX;PYR-FTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS;PYR-FTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS (DISULFIDE BRIDGE: 7-28,13-33 AND 17-35);PYR-PHE-THR-ASN-VAL-SER-CYS-THR-THR-SER-LYS-GLN-CYS-TRP-SER-VAL-CYS-GLN-ARG-LEU-HIS-ASN-THR-SER-ARG-GLY-LYS-CYS-MET-ASN-LYS-LYS-CYS-ARG-CYS-TYR-SER-OH

Price1 Properties Safety Information Description

1 prices

Selected condition：

Brand

Sigma-Aldrich(India)

Package

0.1MG

ManufacturerSigma-Aldrich(India)
Product numberC7802
Product descriptionCharybdotoxin ≥90% (HPLC)
Packaging0.1MG
Price₹54384.8
Updated2022-06-14
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Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	C7802	Charybdotoxin ≥90% (HPLC)	0.1MG	₹54384.8	2022-06-14	Buy

Properties

RTECS :FL7535000
storage temp. :-20°C
form :lyophilized powder
Water Solubility :Soluble to 1 mg/ml in water

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H312	Harmful in contact with skin	Acute toxicity,dermal	Category 4	Warning	P280,P302+P352, P312, P322, P363,P501
H332	Harmful if inhaled	Acute toxicity,inhalation	Category 4	Warning	P261, P271, P304+P340, P312

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P322	Specific measures (see …on this label).
P330	Rinse mouth.
P363	Wash contaminated clothing before reuse.
P501	Dispose of contents/container to..…

Description

Charybdotoxin is a peptide found in the venom of the scorpion Leiurus quinquestriatus. MaxiK (High, BK) or IK1 (intermediate) conductance calcium-activated and Kv1.3 (voltage-gated channel) inhibitor. A potent and selective blocker of the large conductance Ca²⁺-activated K⁺, Slo channels in nanomolar concentrations as well as Kv1.2 (Kd = 14 nM) and Kv1.3 (Kd = 2.6 nM) channels. Present in GH3 anterior pituitary cells and primary bovine aortic smooth muscle cells.

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