CK-0157869

₹11961.63 - ₹47781.55
Product name: CK-0157869
CAS: 388592-44-7
MF: C17H16BrNO3S
MW: 394.28
EINECS:
MDL Number:MFCD01844129
Synonyms:2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone;CK 869;CK-0157869;CK-869;CS-2870;CK-869; CK 869; CK869; CK-0157869; CK 0157869; CK0157869;4-Thiazolidinone, 2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-;CK869,Arp2/3 Complex,inhibit,CK-869,Inhibitor,CK 869,Actin-related protein 2/3 complex

Price2 Properties Safety Information Description

2 prices

Selected condition：

Brand

Sigma-Aldrich(India)

Package

5MG
25MG

ManufacturerSigma-Aldrich(India)
Product numberC9124
Product descriptionCK-869 ≥98% (HPLC)
Packaging5MG
Price₹11961.63
Updated2022-06-14
Buy

ManufacturerSigma-Aldrich(India)
Product numberC9124
Product descriptionCK-869 ≥98% (HPLC)
Packaging25MG
Price₹47781.55
Updated2022-06-14
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	C9124	CK-869 ≥98% (HPLC)	5MG	₹11961.63	2022-06-14	Buy
Sigma-Aldrich(India)	C9124	CK-869 ≥98% (HPLC)	25MG	₹47781.55	2022-06-14	Buy

Properties

storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
color :white to light gray

Safety Information

Symbol(GHS):

Signal word:

Danger

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H361	Suspected of damaging fertility or the unborn child	Reproductive toxicity	Category 2	Warning	P201, P202, P281, P308+P313, P405,P501
H372	Causes damage to organs through prolonged or repeated exposure	Specific target organ toxicity, repeated exposure	Category 1	Danger	P260, P264, P270, P314, P501
H410	Very toxic to aquatic life with long lasting effects	Hazardous to the aquatic environment, long-term hazard	Category 1	Warning	P273, P391, P501

Precautionary statements:

P201	Obtain special instructions before use.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.

Description

CK 869 is an inhibitor of actin polymerization via inhibition of the actin-related protein 2/3 (Arp2/3) complex, leading to reduced cell motility rate and rearrangement of F-actin in M-1 cells. It inhibits comet tail formation by L. monocytogenes with an IC₅₀ value of 7 μM. It also impairs cell adhesion and cell spreading in MCF10A human breast epithelial cells.

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