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CLORGYLINE HYDROCHLORIDE

CLORGYLINE HYDROCHLORIDE Structure
  • ₹9677.55 - ₹67537.18
  • Product name: CLORGYLINE HYDROCHLORIDE
  • CAS: 17780-75-5
  • MF: C13H16Cl3NO
  • MW: 308.63
  • EINECS:241-760-5
  • MDL Number:MFCD00052012
  • Synonyms:CLORGYLINE HYDROCHLORIDE;N-METHYL-N-PROPARGYL-3-(2,4-DICHLOROPHENOXY)-PROPYLAMINE HYDROCHLORIDE;3-(2,4-dichlorophenoxy)-n-methyl-n-propargyl-propylaminhydrochloride ;n-(3-(2,4-dichlorophenoxy)propyl)-n-methyl-2-propyn-1-aminhydrochloride ;n-(3-(2,4-dichlorophenoxy)propyl)-n-methyl-2-propynylaminhydrochloride ;N-methyl-N-propargyl-3-(2,4-*dichlorophenoxy)prop;N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-2-propynylamine hydrochloride ;N-METHYL-N-PROPARGYL-3-(2,4-*DICHLOROPHE NOXY)PROPYL
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • 100MG
  • 500MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberM3778
  • Product descriptionN-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride ≥97% (GC)
  • Packaging50MG
  • Price₹9677.55
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM3778
  • Product descriptionN-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride ≥97% (GC)
  • Packaging100MG
  • Price₹17265.88
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberM3778
  • Product descriptionN-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride ≥97% (GC)
  • Packaging500MG
  • Price₹67537.18
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) M3778 N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride ≥97% (GC) 50MG ₹9677.55 2022-06-14 Buy
Sigma-Aldrich(India) M3778 N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride ≥97% (GC) 100MG ₹17265.88 2022-06-14 Buy
Sigma-Aldrich(India) M3778 N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride ≥97% (GC) 500MG ₹67537.18 2022-06-14 Buy

Properties

storage temp. :2-8°C
solubility :≥17.65 mg/mL in DMSO; ≥18.2 mg/mL in EtOH; ≥24.8 mg/mL in H2O
form :A crystalline solid
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Clorgyline is a potent monoamine oxidase (MAO) inhibitor that preferentially targets MAO-A over MAO-B (Kis = 0.054 and 58 μM, respectively). This inhibition is irreversible. Clorgyline is without effect on serotonin receptors, but it does inhibit the sigma receptor σ1 on Jurkat human T lymphocyte cells (IC50 = 31 nM). As MAO-A preferentially oxidizes serotonin, selective MAO-A inhibitors have applications in ameliorating depression and anxiety.

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