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ChemicalBook > Product Catalogue >Biochemical Engineering >Nucleoside drugs >Deoxynucleotides and their analogs >Capecitabine

Capecitabine

Capecitabine Structure
  • ₹5693.95 - ₹17320
  • Product name: Capecitabine
  • CAS: 154361-50-9
  • MF: C15H22FN3O6
  • MW: 359.35
  • EINECS:604-948-1
  • MDL Number:MFCD00930626
  • Synonyms:Capcitabine;5'-DEOXY-5-FLUOROCYTISINE;5'-DEOXY-5-FLUORO-N-[(PENTYLOXY)CARBONYL]CYTIDINE;Pentyl (1-((2R,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydr;RO-9-1978;pentyl [1-(3,4-dihydroxy-5-methyl-oxolan-2-yl)-5-fluoro-2-oxo-pyrimidin-4-yl]aminoformate;XELODA;CAPECITABINE
6 prices
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Brand

  • Sigma-Aldrich(India)
  • TCI Chemicals (India)

Package

  • 10MG
  • 50MG
  • 1ML
  • 1G
  • 5G
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0653
  • Product descriptionCapecitabine ≥98% (HPLC)
  • Packaging10MG
  • Price₹5693.95
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1405
  • Product descriptionCapecitabine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹9894.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1281
  • Product descriptionCapecitabine Ready Made Solution 10?mg/mL in DMSO
  • Packaging1ML
  • Price₹17236.8
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0653
  • Product descriptionCapecitabine ≥98% (HPLC)
  • Packaging50MG
  • Price₹17320
  • Updated2022-06-14
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2878
  • Product descriptionCapecitabine
  • Packaging5G
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2878
  • Product descriptionCapecitabine
  • Packaging1G
  • Price₹12400
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0653 Capecitabine ≥98% (HPLC) 10MG ₹5693.95 2022-06-14 Buy
Sigma-Aldrich(India) PHR1405 Capecitabine Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹9894.05 2022-06-14 Buy
Sigma-Aldrich(India) SML1281 Capecitabine Ready Made Solution 10?mg/mL in DMSO 1ML ₹17236.8 2022-06-14 Buy
Sigma-Aldrich(India) SML0653 Capecitabine ≥98% (HPLC) 50MG ₹17320 2022-06-14 Buy
TCI Chemicals (India) C2878 Capecitabine 5G ₹14500 2022-05-26 Buy
TCI Chemicals (India) C2878 Capecitabine 1G ₹12400 2022-05-26 Buy

Properties

Melting point :110-121°C
Density :1.49±0.1 g/cm3(Predicted)
Flash point :87℃
storage temp. :2-8°C
solubility :H2O: soluble10mg/mL, clear (warmed)
pka :5.41±0.40(Predicted)
form :powder
color :white to beige
Merck :14,1754
InChI :InChI=1S/C15H22FN3O6/c1-3-4-5-6-24-15(23)18-12-9(16)7-19(14(22)17-12)13-11(21)10(20)8(2)25-13/h7-8,10-11,13,20-21H,3-6H2,1-2H3,(H,17,18,22,23)/t8-,10-,11-,13-/m1/s1
InChIKey :GAGWJHPBXLXJQN-UORFTKCHSA-N
SMILES :C[C@H]1O[C@@H](N2C=C(F)C(NC(OCCCCC)=O)=NC2=O)[C@H](O)[C@@H]1O
CAS DataBase Reference :154361-50-9(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

5-Fluorouracil (5-FU) is a pyrimidine analog which noncompetitively inhibits thymidylate synthase, interfering with DNA synthesis. It has been used for the treatment of cancer for several decades. Capecitabine is a fluoropyrimidine carbamate which acts as a prodrug, being enzymatically converted to 5-FU by enzymes concentrated in the liver and in cancer tissue. The selective localization of these processing enzymes, and in particular, thymidine phosphorylase in tumor tissues, targets the production of the active product, 5-FU, in cancer cells.

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