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ChemicalBook > Product Catalogue >API >Antibiotics >Cephalosporins Drugs >Ceftibuten dihydrate

Ceftibuten dihydrate

Ceftibuten dihydrate Structure
  • ₹0
  • Product name: Ceftibuten dihydrate
  • CAS: 118081-34-8
  • MF: C15H16N4O7S2
  • MW: 428.43
  • EINECS:
  • MDL Number:MFCD08141796
  • Synonyms:Cedax dihydrate;CEDAX DIHYDRATE;SCH-39720 DIHYDRATE;Sch-39720 dihydrate;(+)-(6r,7r)-7-[2-(2-amino-1,3-thiazol-4-yl)-4-carboxy-2-butenamide]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrate;Cedax;Cedax (tn);Ceftibuten (jp15);Cetb
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Properties

Melting point :>180°C (dec.)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO (Slightly), Water (Slightly)
form :Solid
color :Pale Yellow to Light Orange
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P235 Keep cool.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Ceftibuten Dihydrate is the dihydrate form of ceftibuten, a semisynthetic, beta-lactamase-stable, third-generation cephalosporin with antibacterial activity. Ceftibuten binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

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