Cisatracurium besylate
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- Product name: Cisatracurium besylate
- CAS: 96946-42-8
- MF: C53H72N2O12.2C6H5O3S
- MW: 1243.49
- EINECS:620-579-9
- MDL Number:MFCD00871018
- Synonyms:(1r,1'r,2r,2'r)-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium dibenzenesulfonate;cisatracurium besylate;1R-CIS,1R∧-CIS (CISATRACURIUM BESYLATE);Cisatrcurium Besylate;3-[(1R,2R)-6,7-dimethoxy-2-methyl-1-veratryl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propionic acid 5-[3-[(1R,2R)-6,7-dimethoxy-2-methyl-1-veratryl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl ester;5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate;Cisatracurium besyla;Cisatracurium bes (Cisatracuriumbesylate/Clotrimazole)
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Properties
Melting point :90-93°C
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :H2O: soluble1mg/mL
form :Powder
color :white
InChIKey :XXZSQOVSEBAPGS-UHFFFAOYSA-L
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :H2O: soluble1mg/mL
form :Powder
color :white
InChIKey :XXZSQOVSEBAPGS-UHFFFAOYSA-L
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Cisatracurium besylate is a new intermediate-duration non-depolarizing muscle relaxant launched in the U.S.A. for intubation and maintenance of muscle relaxation during surgery and intensive care. Cisatracurium besylate is the single 1 R cis-1'R cis isomer of the commercial preparation of atracurium, a mixture of 10 isomers. It is 3 to 5 times more potent than the mixture with similar onset and duration of action. The single isomer was also reported to have reduced propensity to release histamine and have a stable cardiovascular profile. Similar to structurally related mivacurium, cisatracurium has distinct advantages of rapid degradation, enzymatic metabolism that is independent of liver or kidney resulting in short duration of action and fast, complete recovery.More related product prices
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