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ChemicalBook > Product Catalogue >Biochemical Engineering >nucleic acid drugs >Citicoline sodium

Citicoline sodium

Citicoline sodium Structure
  • ₹2200 - ₹50769.25
  • Product name: Citicoline sodium
  • CAS: 33818-15-4
  • MF: C14H26N4O11P2.Na
  • MW: 511.31
  • EINECS:251-689-1
  • MDL Number:MFCD00037486
  • Synonyms:P'-[2-(TRIMETHYLAMMONIO)ETHYL]ESTER CYTIDINE 5'-(TRIHYDROGEN DIPHOSPHATE) INNER SALT MONOSODIUM;cytidine 5'-(trihydrogen diphosphate) p'-[2-(trimethylammonio)ethyl] ester inner salt monosodium salt;CYTIDINE-5'-DIPHOSPHOCHOLINE MONOSODIUM SALT;CYTIDINE-5'-DIPHOSPHOCHOLINE, NA;CYTIDINE-5'-DIPHOSPHOCHOLINE, SODIUM;CYTIDINE 5'-DIPHOSPHOCHOLINE SODIUM SALT;CYTIDINE 5'-DIPHOSPHOCHOLINE SODIUM SALT DIHYDRATE;CITICOLINE SODIUM
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Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 100MG
  • 250MG
  • 500MG
  • 1G
  • 5G
  • 10g
  • 25g
  • 50g
  • ManufacturerALFA India
  • Product numberALF-J64161-09
  • Product descriptionThermo Scientific™ Cytidine-5'-diphosphocholine sodium salt
  • Packaging10g
  • Price₹5625
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J64161-14
  • Product descriptionThermo Scientific™ Cytidine-5'-diphosphocholine sodium salt
  • Packaging25g
  • Price₹11159
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-J64161-18
  • Product descriptionThermo Scientific™ Cytidine-5'-diphosphocholine sodium salt
  • Packaging50g
  • Price₹22260
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3445
  • Product descriptionCytidine 5'-Diphosphocholine Sodium Salt
  • Packaging1G
  • Price₹2200
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3445
  • Product descriptionCytidine 5'-Diphosphocholine Sodium Salt
  • Packaging5G
  • Price₹2600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC0256
  • Product descriptionCytidine 5′-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid
  • Packaging100MG
  • Price₹10002.3
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number34015
  • Product descriptionCiticoline sodium salt hydrate VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹10283.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number30290
  • Product descriptionCytidine 5′-diphosphocholine sodium salt hydrate ≥99.0% (HPLC)
  • Packaging250MG
  • Price₹11615.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC0256
  • Product descriptionCytidine 5′-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid
  • Packaging500MG
  • Price₹27679.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number30290
  • Product descriptionCytidine 5′-diphosphocholine sodium salt hydrate ≥99.0% (HPLC)
  • Packaging1G
  • Price₹38450.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC0256
  • Product descriptionCytidine 5′-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid
  • Packaging1G
  • Price₹50769.25
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-J64161-09 Thermo Scientific™ Cytidine-5'-diphosphocholine sodium salt 10g ₹5625 2022-05-26 Buy
ALFA India ALF-J64161-14 Thermo Scientific™ Cytidine-5'-diphosphocholine sodium salt 25g ₹11159 2022-05-26 Buy
ALFA India ALF-J64161-18 Thermo Scientific™ Cytidine-5'-diphosphocholine sodium salt 50g ₹22260 2022-05-26 Buy
TCI Chemicals (India) C3445 Cytidine 5'-Diphosphocholine Sodium Salt 1G ₹2200 2022-05-26 Buy
TCI Chemicals (India) C3445 Cytidine 5'-Diphosphocholine Sodium Salt 5G ₹2600 2022-05-26 Buy
Sigma-Aldrich(India) C0256 Cytidine 5′-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid 100MG ₹10002.3 2022-06-14 Buy
Sigma-Aldrich(India) 34015 Citicoline sodium salt hydrate VETRANAL?, analytical standard 100MG ₹10283.75 2022-06-14 Buy
Sigma-Aldrich(India) 30290 Cytidine 5′-diphosphocholine sodium salt hydrate ≥99.0% (HPLC) 250MG ₹11615.23 2022-06-14 Buy
Sigma-Aldrich(India) C0256 Cytidine 5′-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid 500MG ₹27679.53 2022-06-14 Buy
Sigma-Aldrich(India) 30290 Cytidine 5′-diphosphocholine sodium salt hydrate ≥99.0% (HPLC) 1G ₹38450.4 2022-06-14 Buy
Sigma-Aldrich(India) C0256 Cytidine 5′-diphosphocholine sodium salt dihydrate ~98%, from yeast, solid 1G ₹50769.25 2022-06-14 Buy

Properties

Melting point :259-268°C (dec.)
alpha :D20 +12.5° (c = 1.0 in H2O)
storage temp. :-20°C
solubility :H2O: 100mg/mL
form :solid
color :white
Water Solubility :Soluble in water (100 mg/ml).
λmax :280nm(HCl aq.)(lit.)
Merck :13,2343
BRN :4110040
InChIKey :YWAFNFGRBBBSPD-OCMLZEEQSA-M
SMILES :O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP([O-])(=O)OCC[N+](C)(C)C)O[C@H]1N1C=CC(N)=NC1=O)O.[NaH] |&1:1,2,3,21,r|
CAS DataBase Reference :33818-15-4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.

Description

Citicoline is a nucleic acid derivatives, Geiger found that citicoline can restore brain injury in the animal experiments in 1956. Kennedy study confirmed that citicoline can make brain injury recovery in 1957. Takeda pharmaceutical company in Japan developed and produced it in 1961. It was registered in China in 1988, and is currently the best-selling drug among clinical brain diseases. It plays an important role in the synthesis of lecithin, by promoting the synthesis of lecithin and improving brain function. Experiments show that citicoline can enhance the levels of norepinephrine and dopamine in the central nervous system, thereby it can treat cerebrovascular disease, traumatic brain injury and cognitive impairment caused by various reasons, and there are no obvious side effects.
Citicoline sodium can enhance the function of brain stem reticular formation, especially the ascending reticular activating system associated with human consciousness; enhance the function of the pyramidal system; inhibit the function of the external system of the cone, and promotes the recovery of the function of the system. For the treatment of sequelae of traumatic brain injury and cerebral vascular accident caused by the nervous system, it can also be used in the treatment of Parkinson's disease, senile dementia has a certain effect; for the treatment of cardiovascular and cerebrovascular diseases; it also have a certain effect for anti-aging, improving learning and memory.

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