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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Natural sources of antineoplastic >Colchicine

Colchicine

Colchicine Structure
  • ₹1656 - ₹137536
  • Product name: Colchicine
  • CAS: 64-86-8
  • MF: C22H25NO6
  • MW: 399.44
  • EINECS:200-598-5
  • MDL Number:MFCD00078484
  • Synonyms:N-((S)-1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL)-ACETAMIDE;n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-acetamide;len-7-yl)- ;N-(1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide;n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-acetamid ;n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-acetamid ;N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)-,(S)-Acetamide ;n-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamid
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  • Sigma-Aldrich(India)
  • TCI Chemicals (India)
  • ALFA India
  • ottokemi
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  • 1G
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  • ManufacturerSigma-Aldrich(India)
  • Product numberC9754
  • Product descriptionColchicine ≥95% (HPLC), powder
  • Packaging100MG
  • Price₹2998.53
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberC9754
  • Product descriptionColchicine ≥95% (HPLC), powder
  • Packaging500MG
  • Price₹5758.9
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberC9754
  • Product descriptionColchicine ≥95% (HPLC), powder
  • Packaging1G
  • Price₹7057.9
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number234115
  • Product descriptionColchicine, Colchicum autumnale - CAS 64-86-8 - Calbiochem Colchicine, Colchicum autumnale, CAS 64-86-8, is an inhibitor of mitosis that disrupts microtubules and inhibits tubulin polymerization. Induces apopt
  • Packaging1G
  • Price₹9380
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberC3915
  • Product descriptionColchicine BioReagent, suitable for plant cell culture, ≥95% (HPLC)
  • Packaging500MG
  • Price₹9948.18
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1764
  • Product descriptionColchicine Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging400MG
  • Price₹16215.85
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberC3915
  • Product descriptionColchicine BioReagent, suitable for plant cell culture, ≥95% (HPLC)
  • Packaging1G
  • Price₹16432.35
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberC9754
  • Product descriptionColchicine ≥95% (HPLC), powder
  • Packaging5G
  • Price₹28718.73
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number234115
  • Product descriptionColchicine, Colchicum autumnale - CAS 64-86-8 - Calbiochem Colchicine, Colchicum autumnale, CAS 64-86-8, is an inhibitor of mitosis that disrupts microtubules and inhibits tubulin polymerization. Induces apopt
  • Packaging5G
  • Price₹61420
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberC3915
  • Product descriptionColchicine BioReagent, suitable for plant cell culture, ≥95% (HPLC)
  • Packaging5G
  • Price₹63023.15
  • Updated2022-06-14
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  • ManufacturerTCI Chemicals (India)
  • Product numberC0380
  • Product descriptionColchicine (contains 5% Ethyl Acetate at maximum)
  • Packaging500MG
  • Price₹3600
  • Updated2022-05-26
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  • ManufacturerTCI Chemicals (India)
  • Product numberC0380
  • Product descriptionColchicine (contains 5% Ethyl Acetate at maximum)
  • Packaging5G
  • Price₹15700
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-A13240-14
  • Product descriptionColchicine, 95% (dry wt.)
  • Packaging25g
  • Price₹137536
  • Updated2022-05-26
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  • ManufacturerALFA India
  • Product numberALF-A13240-06
  • Product descriptionColchicine, 95% (dry wt.)
  • Packaging5g
  • Price₹17766
  • Updated2022-05-26
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  • ManufacturerALFA India
  • Product numberALF-A13240-03
  • Product descriptionColchicine, 95% (dry wt.)
  • Packaging1g
  • Price₹5014
  • Updated2022-05-26
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  • Manufacturerottokemi
  • Product number C 3465
  • Product descriptionColchicine 98%
  • Packaging1gm
  • Price₹1656
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) C9754 Colchicine ≥95% (HPLC), powder 100MG ₹2998.53 2022-06-14 Buy
Sigma-Aldrich(India) C9754 Colchicine ≥95% (HPLC), powder 500MG ₹5758.9 2022-06-14 Buy
Sigma-Aldrich(India) C9754 Colchicine ≥95% (HPLC), powder 1G ₹7057.9 2022-06-14 Buy
Sigma-Aldrich(India) 234115 Colchicine, Colchicum autumnale - CAS 64-86-8 - Calbiochem Colchicine, Colchicum autumnale, CAS 64-86-8, is an inhibitor of mitosis that disrupts microtubules and inhibits tubulin polymerization. Induces apopt 1G ₹9380 2022-06-14 Buy
Sigma-Aldrich(India) C3915 Colchicine BioReagent, suitable for plant cell culture, ≥95% (HPLC) 500MG ₹9948.18 2022-06-14 Buy
Sigma-Aldrich(India) PHR1764 Colchicine Pharmaceutical Secondary Standard; Certified Reference Material 400MG ₹16215.85 2022-06-14 Buy
Sigma-Aldrich(India) C3915 Colchicine BioReagent, suitable for plant cell culture, ≥95% (HPLC) 1G ₹16432.35 2022-06-14 Buy
Sigma-Aldrich(India) C9754 Colchicine ≥95% (HPLC), powder 5G ₹28718.73 2022-06-14 Buy
Sigma-Aldrich(India) 234115 Colchicine, Colchicum autumnale - CAS 64-86-8 - Calbiochem Colchicine, Colchicum autumnale, CAS 64-86-8, is an inhibitor of mitosis that disrupts microtubules and inhibits tubulin polymerization. Induces apopt 5G ₹61420 2022-06-14 Buy
Sigma-Aldrich(India) C3915 Colchicine BioReagent, suitable for plant cell culture, ≥95% (HPLC) 5G ₹63023.15 2022-06-14 Buy
TCI Chemicals (India) C0380 Colchicine (contains 5% Ethyl Acetate at maximum) 500MG ₹3600 2022-05-26 Buy
TCI Chemicals (India) C0380 Colchicine (contains 5% Ethyl Acetate at maximum) 5G ₹15700 2022-05-26 Buy
ALFA India ALF-A13240-14 Colchicine, 95% (dry wt.) 25g ₹137536 2022-05-26 Buy
ALFA India ALF-A13240-06 Colchicine, 95% (dry wt.) 5g ₹17766 2022-05-26 Buy
ALFA India ALF-A13240-03 Colchicine, 95% (dry wt.) 1g ₹5014 2022-05-26 Buy
ottokemi C 3465 Colchicine 98% 1gm ₹1656 2022-05-26 Buy

Properties

Melting point :150-160 °C (dec.)(lit.)
alpha :-250 º (c=1, alcohol)
Boiling point :522.37°C (rough estimate)
Density :1.2770 (rough estimate)
refractive index :1.5614 (estimate)
storage temp. :2-8°C
solubility :H2O: 10 mg/mL
pka :12.36(at 20℃)
form :powder
color :white to yellow with a green cast
Water Solubility :45 g/L (20 ºC)
Sensitive :Light Sensitive
Merck :14,2471
BRN :2228813
BCS Class :3
Stability :Stable. Light sensitive. Incompatible with strong oxidizing agents.
InChIKey :IAKHMKGGTNLKSZ-INIZCTEOSA-N
LogP :1.300
CAS DataBase Reference :64-86-8(CAS DataBase Reference)
NIST Chemistry Reference :Colchicine(64-86-8)
EPA Substance Registry System :Colchicine (64-86-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.

Description

Colchicine is used as an anti-inflammatory agent for long-term treatment of beh?et's disease. It is used for constipation-predominant irritable bowel syndrome in women, and for treatment of severe or persistent aphthous stomatitis (canker sores).

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