DESMETHYL SILDENAFIL
![]() |
- ₹0
- Product name: DESMETHYL SILDENAFIL
- CAS: 139755-82-1
- MF: C21H28N6O4S
- MW: 460.55
- EINECS:
- MDL Number:MFCD00908398
- Synonyms:DESMETHYL SILDENAFIL;5-[2-Ethoxy-5-(1-piperazinylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propyl- 7H-pyrazolo[4,3-d]pyrimidin-7-one;UK 103320;Sildenafil N-DesMethyl IMpurity;5-(2-Ethoxy-5-(piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one;Sildenafil N-desmethyl;Sildenafil N-desmethy impurity;Sildenafil EP Impurity F (Sildenafil N-Desmethyl Metabolite)
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|
Properties
Melting point :158-160°C
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.15 mg/ml
form :A crystalline solid
pka :10.05±0.20(Predicted)
color :White to off-white
Stability :Moisture Sensitive
Density :1.44±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMF: 5 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.15 mg/ml
form :A crystalline solid
pka :10.05±0.20(Predicted)
color :White to off-white
Stability :Moisture Sensitive
Safety Information
Symbol(GHS): |
![]() |
|||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | |||||||||||||||||||||||||||||||||||
Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Sildenafil is a potent cGMP-specific phosphodiesterase (PDE) inhibitor that is highly selective for PDE5 (IC50 = 3.6 nM). Inhibition of PDE5 prolongs nitric oxide-mediated relaxation of smooth muscle in a range of vascular tissues. N-Desmethyl sildenafil is a major metabolite of sildenafil. The conversion of sildenafil to this metabolite is affected by age and by renal and hepatic impairment.Related product price
- 139756-01-7
₹10100-31900 - 139756-02-8
₹10800-19500 - Sildenafil
₹10041.5